Three-stage ex vivo expansion of high-ploidy megakaryocytic cells: toward large-scale platelet production.
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Stem cells, megakaryocytes, and plateletsAre Platelets Cells? And if Yes, are They Immune Cells?Synergistic effect of hydrogen peroxide on polyploidization during the megakaryocytic differentiation of K562 leukemia cells by PMA.Safety and Efficacy of Megakaryocytes Induced from Hematopoietic Stem Cells in Murine and Nonhuman Primate ModelsShear enhances thrombopoiesis and formation of microparticles that induce megakaryocytic differentiation of stem cells.Human megakaryocyte progenitors derived from hematopoietic stem cells of normal individuals are MHC class II-expressing professional APC that enhance Th17 and Th1/Th17 responses.Phenotypic and functional comparison of mobilized peripheral blood versus umbilical cord blood megakaryocyte populations.The use of covalently immobilized stem cell factor to selectively affect hematopoietic stem cell activity within a gelatin hydrogelMicrofluidic assessment of functional culture-derived platelets in human thrombi under flow.Megakaryocytic Maturation in Response to Shear Flow Is Mediated by the Activator Protein 1 (AP-1) Transcription Factor via Mitogen-activated Protein Kinase (MAPK) Mechanotransduction.Applications of human hematopoietic stem cells isolated and expanded from different tissues in regenerative medicine.Megakaryocyte Polyploidization and Proplatelet Formation in Low-Attachment Conditions.Recent developments in ex vivo platelet production.Aryl hydrocarbon receptor-dependent enrichment of a megakaryocytic precursor with a high potential to produce proplatelets.Proliferation extent of CD34+ cells as a key parameter to maximize megakaryocytic differentiation of umbilical cord blood-derived hematopoietic stem/progenitor cells in a two-stage culture protocol.Separation of in-vitro-derived megakaryocytes and platelets using spinning-membrane filtration.Small Molecule Supplements Improve Cultured Megakaryocyte Polyploidization by Modulating Multiple Cell Cycle Regulators.Large-scale culture of a megakaryocytic progenitor cell line with a single-use bioreactor system.A uniform-shear rate microfluidic bioreactor for real-time study of proplatelet formation and rapidly-released platelets.Producing megakaryocytes from a human peripheral blood source.How do megakaryocytic microparticles target and deliver cargo to alter the fate of hematopoietic stem cells?Engineering human megakaryocytic microparticles for targeted delivery of nucleic acids to hematopoietic stem and progenitor cellsRole of p53 and transcription-independent p53-induced apoptosis in shear-stimulated megakaryocytic maturation, particle generation, and platelet biogenesis
P2860
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P2860
Three-stage ex vivo expansion of high-ploidy megakaryocytic cells: toward large-scale platelet production.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Three-stage ex vivo expansion ...... rge-scale platelet production.
@en
type
label
Three-stage ex vivo expansion ...... rge-scale platelet production.
@en
prefLabel
Three-stage ex vivo expansion ...... rge-scale platelet production.
@en
P2093
P2860
P1476
Three-stage ex vivo expansion ...... rge-scale platelet production.
@en
P2093
Alaina C Schlinker
Eleftherios T Papoutsakis
Paul F Lindholm
Swapna Panuganti
P2860
P304
P356
10.1089/TEN.TEA.2011.0111
P577
2013-01-14T00:00:00Z