A novel mutant topoisomerase II alpha present in VP-16-resistant human melanoma cell lines has a deletion of alanine 429.
about
Modulation of drug sensitivity in yeast cells by the ATP-binding domain of human DNA topoisomerase IIalphaEffect of transfection of a Drosophila topoisomerase II gene into a human brain tumour cell line intrinsically resistant to etoposide.Ectopic expression of inactive forms of yeast DNA topoisomerase II confers resistance to the anti-tumour drug, etoposide.Characterization of human NSCLC cell line with innate etoposide-resistance mediated by cytoplasmic localization of topoisomerase II alpha.A truncated cytoplasmic topoisomerase IIalpha in a drug-resistant lung cancer cell line is encoded by a TOP2A allele with a partial deletion of exon 34.Verapamil suppresses the emergence of P-glycoprotein-mediated multi-drug resistance.Modulation of DNA topoisomerase II activity and expression in melanoma cells with acquired drug resistance.Hypophosphorylation of topoisomerase IIalpha in etoposide (VP-16)-resistant human carcinoma cell lines associated with carboxy-terminal truncation.
P2860
Q36118901-A9C8D56D-CCC6-45A8-BA85-7CEE05FE0631Q36135162-18D34360-2FAA-40B4-AE67-E57AE1005278Q36135236-235D45A0-2926-4D48-ACB9-CF60A1441280Q40354662-A4D4E045-5B40-4F10-B95E-6E2B71FE59FBQ40896279-DFB62F22-706B-4832-BB3C-BDCC085D4E96Q41198255-BDB6002A-0C64-47DA-A2EB-D706C280B1A2Q41899243-62CDEE0F-144A-45E6-BDB7-BA56E9EA30DEQ43688398-E84A50B7-0C41-4CE7-9030-D09435DAA667
P2860
A novel mutant topoisomerase II alpha present in VP-16-resistant human melanoma cell lines has a deletion of alanine 429.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
A novel mutant topoisomerase I ...... has a deletion of alanine 429.
@en
type
label
A novel mutant topoisomerase I ...... has a deletion of alanine 429.
@en
prefLabel
A novel mutant topoisomerase I ...... has a deletion of alanine 429.
@en
P2093
P356
P1433
P1476
A novel mutant topoisomerase I ...... has a deletion of alanine 429.
@en
P2093
Campain JA
Gottesman MM
P304
11327-11332
P356
10.1021/BI00203A030
P407
P577
1994-09-01T00:00:00Z