Mrc1 and Srs2 are major actors in the regulation of spontaneous crossover.
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Cdk1 targets Srs2 to complete synthesis-dependent strand annealing and to promote recombinational repairThe RecQ DNA helicases in DNA repairMeiotic versus mitotic recombination: two different routes for double-strand break repair: the different functions of meiotic versus mitotic DSB repair are reflected in different pathway usage and different outcomesComparative genomics and molecular dynamics of DNA repeats in eukaryotesMechanisms and regulation of mitotic recombination in Saccharomyces cerevisiaeYeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic recombination.Nej1 recruits the Srs2 helicase to DNA double-strand breaks and supports repair by a single-strand annealing-like mechanism.Interplay between the Smc5/6 complex and the Mph1 helicase in recombinational repairSrs2 mediates PCNA-SUMO-dependent inhibition of DNA repair synthesis.Mrc1 and Tof1 regulate DNA replication forks in different ways during normal S phaseEsc2 and Sgs1 act in functionally distinct branches of the homologous recombination repair pathway in Saccharomyces cerevisiae.Srs2 promotes Mus81-Mms4-mediated resolution of recombination intermediates.Rad52 sumoylation prevents the toxicity of unproductive Rad51 filaments independently of the anti-recombinase Srs2Elevated histone expression promotes life span extensionMeiotic chromosome synapsis-promoting proteins antagonize the anti-crossover activity of sgs1.Srs2 promotes synthesis-dependent strand annealing by disrupting DNA polymerase δ-extending D-loopsDistinct Cdk1 requirements during single-strand annealing, noncrossover, and crossover recombination.Visualization of recombination-mediated damage bypass by template switching.The chromatin assembly factor 1 promotes Rad51-dependent template switches at replication forks by counteracting D-loop disassembly by the RecQ-type helicase Rqh1Unwinding of synthetic replication and recombination substrates by Srs2.Continued DNA synthesis in replication checkpoint mutants leads to fork collapse.Mus81 and Yen1 promote reciprocal exchange during mitotic recombination to maintain genome integrity in budding yeast.Heteroduplex DNA position defines the roles of the Sgs1, Srs2, and Mph1 helicases in promoting distinct recombination outcomes.Srs2 overexpression reveals a helicase-independent role at replication forks that requires diverse cell functionsTop3-Rmi1 dissolve Rad51-mediated D loops by a topoisomerase-based mechanism.Multiple regulation of Rad51-mediated homologous recombination by fission yeast Fbh1.SRS2 and SGS1 prevent chromosomal breaks and stabilize triplet repeats by restraining recombination.Mechanism of DNA damage tolerance.Srs2 and Mus81-Mms4 Prevent Accumulation of Toxic Inter-Homolog Recombination Intermediates.Local regulation of the Srs2 helicase by the SUMO-like domain protein Esc2 promotes recombination at sites of stalled replication.The human F-Box DNA helicase FBH1 faces Saccharomyces cerevisiae Srs2 and postreplication repair pathway roles.Sequence divergence impedes crossover more than noncrossover events during mitotic gap repair in yeast.Srs2 removes deadly recombination intermediates independently of its interaction with SUMO-modified PCNARad51 gain-of-function mutants that exhibit high affinity DNA binding cause DNA damage sensitivity in the absence of Srs2.Break-induced replication occurs by conservative DNA synthesisThe Saccharomyces cerevisiae Esc2 and Smc5-6 proteins promote sister chromatid junction-mediated intra-S repair.Suppression of the double-strand-break-repair defect of the Saccharomyces cerevisiae rad57 mutantMRE11 complex links RECQ5 helicase to sites of DNA damage.Resolution by unassisted Top3 points to template switch recombination intermediates during DNA replication.Readers of PCNA modifications
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Mrc1 and Srs2 are major actors in the regulation of spontaneous crossover.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Mrc1 and Srs2 are major actors in the regulation of spontaneous crossover.
@en
type
label
Mrc1 and Srs2 are major actors in the regulation of spontaneous crossover.
@en
prefLabel
Mrc1 and Srs2 are major actors in the regulation of spontaneous crossover.
@en
P2093
P2860
P356
P1433
P1476
Mrc1 and Srs2 are major actors in the regulation of spontaneous crossover.
@en
P2093
Delphine Dervins
Francis Fabre
Serge Gangloff
Thomas Robert
P2860
P304
P356
10.1038/SJ.EMBOJ.7601158
P407
P577
2006-05-25T00:00:00Z