WWP2 ubiquitin ligase and its isoforms: new biological insight and promising disease targets.
about
A design principle underlying the paradoxical roles of E3 ubiquitin ligasesRegulation of glioma migration and invasion via modification of Rap2a activity by the ubiquitin ligase Nedd4-1.WWP2 is overexpressed in human oral cancer, determining tumor size and poor prognosis in patients: downregulation of WWP2 inhibits the AKT signaling and tumor growth in mice.Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 proteinWWP2 and its association with PTEN in endometrial cancerCrosstalk between kinases and Nedd4 family ubiquitin ligases.Silencing of WWP2 inhibits adhesion, invasion, and migration in liver cancer cells.Paip1, an effective stimulator of translation initiation, is targeted by WWP2 for ubiquitination and degradationWWP2-WWP1 ubiquitin ligase complex coordinated by PPM1G maintains the balance between cellular p73 and ΔNp73 levels.Differential role of PTEN in transforming growth factor β (TGF-β) effects on proliferation and migration in prostate cancer cells.
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WWP2 ubiquitin ligase and its isoforms: new biological insight and promising disease targets.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
WWP2 ubiquitin ligase and its ...... and promising disease targets.
@en
type
label
WWP2 ubiquitin ligase and its ...... and promising disease targets.
@en
prefLabel
WWP2 ubiquitin ligase and its ...... and promising disease targets.
@en
P2860
P356
P1433
P1476
WWP2 ubiquitin ligase and its ...... and promising disease targets.
@en
P2093
Andrew Chantry
P2860
P304
P356
10.4161/CC.10.15.16874
P577
2011-08-01T00:00:00Z