Guam amyotrophic lateral sclerosis-parkinsonism-dementia linked to a plant excitant neurotoxin.
about
Dietary BMAA exposure in an amyotrophic lateral sclerosis cluster from southern FranceMaternal transfer of the cyanobacterial neurotoxin β-N-methylamino-L-alanine (BMAA) via milk to suckling offspringVisual signs and symptoms of Parkinson's diseaseThe emerging science of BMAA: do cyanobacteria contribute to neurodegenerative disease?The gene encoding the glutamate receptor subunit GluR5 is located on human chromosome 21q21.1-22.1 in the vicinity of the gene for familial amyotrophic lateral sclerosisCyanobacterial blooms and the occurrence of the neurotoxin, beta-N-methylamino-l-alanine (BMAA), in South Florida aquatic food websExpressed sequence tag analysis in Cycas, the most primitive living seed plantChronic Glutamate Toxicity in Neurodegenerative Diseases-What is the Evidence?Is neurodegenerative disease a long-latency response to early-life genotoxin exposure?Intracellular fibril formation, calcification, and enrichment of chaperones, cytoskeletal, and intermediate filament proteins in the adult hippocampus CA1 following neonatal exposure to the nonprotein amino acid BMAADiverse taxa of cyanobacteria produce beta-N-methylamino-L-alanine, a neurotoxic amino acidLong-term cognitive impairments in adult rats treated neonatally with beta-N-Methylamino-L-AlanineDietary exposure to an environmental toxin triggers neurofibrillary tangles and amyloid deposits in the brainBeta-N-methylamino-L-alanine enhances neurotoxicity through multiple mechanismsA mechanism for slow release of biomagnified cyanobacterial neurotoxins and neurodegenerative disease in GuamUnraveling 50-Year-Old Clues Linking Neurodegeneration and Cancer to Cycad Toxins: Are microRNAs Common Mediators?Searching for a link between the L-BMAA neurotoxin and amyotrophic lateral sclerosis: a study protocol of the French BMAALS programmeCyanobacterial Neurotoxin BMAA and Mercury in SharksAluminum and chronic renal failure: sources, absorption, transport, and toxicity.Neonatal exposure to the cyanobacterial toxin BMAA induces changes in protein expression and neurodegeneration in adult hippocampusIdentification of novel susceptibility loci for Guam neurodegenerative disease: challenges of genome scans in genetic isolates.Damage and repair of nerve cell DNA in toxic stress.Enantiomeric separation of amino acids and nonprotein amino acids using a particle-loaded monolithic column.Hippocampal and entorhinal cortex neurofibrillary tangle formation in Guamanian Chamorros free of overt neurologic dysfunction.Biophysics of Parkinson's disease: structure and aggregation of alpha-synuclein.Parkinson-dementia complex and development of a new stable isotope dilution assay for BMAA detection in tissueAdult onset motor neuron disease: worldwide mortality, incidence and distribution since 1950.Fragmentation of the Golgi apparatus of motor neurons in amyotrophic lateral sclerosis revealed by organelle-specific antibodiesProgressive medullary failure associated with neurofibrillary degeneration.Current theories on the cause of Parkinson's diseaseTransplantation into the human brain: present status and future possibilities.Central mammalian neurons normally resistant to glutamate toxicity are made sensitive by elevated extracellular Ca2+: toxicity is blocked by the N-methyl-D-aspartate antagonist MK-801Immunoglobulins from amyotrophic lateral sclerosis patients enhance spontaneous transmitter release from motor-nerve terminals.Dementia in Newfoundland: identification of a geographical isolate?Motor neuron disease.Neuroepidemiology of amyotrophic lateral sclerosis: clues to aetiology and pathogenesisA TRPM7 variant shows altered sensitivity to magnesium that may contribute to the pathogenesis of two Guamanian neurodegenerative disorders.High resolution metabolite imaging in the hippocampus following neonatal exposure to the environmental toxin BMAA using ToF-SIMSTransfer of a cyanobacterial neurotoxin within a temperate aquatic ecosystem suggests pathways for human exposureBiomagnification of cyanobacterial neurotoxins and neurodegenerative disease among the Chamorro people of Guam
P2860
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P2860
Guam amyotrophic lateral sclerosis-parkinsonism-dementia linked to a plant excitant neurotoxin.
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
1987年论文
@zh
1987年论文
@zh-cn
name
Guam amyotrophic lateral scler ...... o a plant excitant neurotoxin.
@en
type
label
Guam amyotrophic lateral scler ...... o a plant excitant neurotoxin.
@en
prefLabel
Guam amyotrophic lateral scler ...... o a plant excitant neurotoxin.
@en
P2093
P921
P356
P1433
P1476
Guam amyotrophic lateral scler ...... o a plant excitant neurotoxin.
@en
P2093
Ludolph AC
Robertson RC
Spencer PS
P304
P356
10.1126/SCIENCE.3603037
P407
P577
1987-07-01T00:00:00Z