Molecular cloning, tissue distribution and chromosomal localization of a novel member of the opioid receptor gene family.
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Structure, tissue distribution, and chromosomal localization of the prepronociceptin geneThe evolution of vertebrate opioid receptorsBuprenorphine: a unique drug with complex pharmacologyPharmacology of nociceptin and its receptor: a novel therapeutic targetReceptorphin: a conserved peptide derived from the sequence of the opioid receptor, with opioid displacement activity and potent antiproliferative actions in tumor cellsOrphanin FQ acts as an anxiolytic to attenuate behavioral responses to stressOrphanin FQ/nociceptin attenuates motor stimulation and changes in nucleus accumbens extracellular dopamine induced by cocaine in ratsMolecular Cloning and Characterization of a Novel Form of Neuropeptide Gene as a Developmentally Regulated MoleculeStimulation of sensory neuropeptide release by nociceptin/orphanin FQ leads to hyperaemia in acutely inflamed rat knees.Nociceptin/orphanin FQ suppresses adaptive immune responses in vivo and at picomolar levels in vitro.Mu opioid receptors in pain management.Mode matches and their locations in the hydrophobic free energy sequences of peptide ligands and their receptor eigenfunctionsSearch for the "ideal analgesic" in pain treatment by engineering the mu-opioid receptor.Mutational analysis of the structure and function of opioid receptors.Intrathecal delivery of a mutant micro-opioid receptor activated by naloxone as a possible antinociceptive paradigm.Truncated G protein-coupled mu opioid receptor MOR-1 splice variants are targets for highly potent opioid analgesics lacking side effects.Structure-based virtual screening of the nociceptin receptor: hybrid docking and shape-based approaches for improved hit identification.Opioids and their receptors: Are we there yet?The Nociceptin Receptor as an Emerging Molecular Target for Cocaine AddictionBlockade of mu-opioid receptors reveals the hyperalgesic effect of orphanin FQ/nociceptin in the rat hot plate testNociceptin/orphanin FQ: actions within the brain.Orphanin-FQ/nociceptin: lack of anti nociceptive, hyperalgesic or allodynic effects in acute thermal or mechanical tests following intracerebroventricular or intrathecal administration to mice or rats.Nociceptin effect on intestinal motility depends on opioid-receptor like-1 receptors and nitric oxide synthase co-localization.Estradiol: a key biological substrate mediating the response to cocaine in female ratsCellular mechanisms of nociceptin/orphanin FQ (N/OFQ) peptide (NOP) receptor regulation and heterologous regulation by N/OFQ.Sex differences in the Nociceptin/Orphanin FQ system in rat spinal cord following chronic morphine treatmentMu opioids and their receptors: evolution of a concept.Orphanin FQ/nociceptin suppresses motor activity through an action along the mesoaccumbens axis in ratsUFP-112 a potent and long-lasting agonist selective for the Nociceptin/Orphanin FQ receptor.Enhanced mu-opioid responses in the spinal cord of mice lacking protein kinase Cgamma isoform.Dissociation of affinity and efficacy in KOR-3 chimeras.Nociceptin/orphanin FQ stimulates extracellular acidification and desensitization of the response involves protein kinase C.Molecular characterization and functional expression of opioid receptor-like1 receptor.Identification of dynorphins as endogenous ligands for an opioid receptor-like orphan receptor.Novel Synthesis and Pharmacological Characterization of NOP Receptor Agonist 8-[(1S,3aS)-2,3,3a,4,5,6-Hexahydro-1H-phenalen-1-yl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one (Ro 64-6198)Bradycardia elicited by microinjections of nociceptin/orphanin FQ into the intermediolateral cell column at T1-T2 in the rat.Cloning and expression of a cDNA encoding a mouse brain orphanin FQ/nociceptin precursor.Nociceptin-induced scratching, biting and licking in mice: involvement of spinal NK1 receptors.The interaction of highly helical structural mutants with the NOP receptor discloses the role of the address domain of nociceptin/orphanin FQ.Alterations in the level of OFQ/N-IR in rat brain regions by cocaine.
P2860
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P2860
Molecular cloning, tissue distribution and chromosomal localization of a novel member of the opioid receptor gene family.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Molecular cloning, tissue dist ...... e opioid receptor gene family.
@en
type
label
Molecular cloning, tissue dist ...... e opioid receptor gene family.
@en
prefLabel
Molecular cloning, tissue dist ...... e opioid receptor gene family.
@en
P2093
P2860
P1433
P1476
Molecular cloning, tissue dist ...... e opioid receptor gene family.
@en
P2093
P2860
P304
P356
10.1016/0014-5793(94)00560-5
P407
P577
1994-06-01T00:00:00Z