Mammalian membrane metallopeptidases: NEP, ECE, KELL, and PEX.
about
beta-Amyloid degradation and Alzheimer's diseaseHuman recombinant endopeptidase PHEX has a strict S1' specificity for acidic residues and cleaves peptides derived from fibroblast growth factor-23 and matrix extracellular phosphoglycoproteinDegradation of MEPE, DMP1, and release of SIBLING ASARM-peptides (minhibins): ASARM-peptide(s) are directly responsible for defective mineralization in HYPEndothelinEffect of the inhaled anesthetics isoflurane, sevoflurane and desflurane on the neuropathogenesis of Alzheimer's disease (review)Neutral endopeptidase inhibition and the natriuretic peptide system: an evolving strategy in cardiovascular therapeuticsGeneral anesthetics and β-amyloid proteinRare Variants in MME, Encoding Metalloprotease Neprilysin, Are Linked to Late-Onset Autosomal-Dominant Axonal PolyneuropathiesEndothelin@25 - new agonists, antagonists, inhibitors and emerging research frontiers: IUPHAR Review 12Inhibitors of endopeptidase and angiotensin-converting enzyme lead to an amplification of the morphological changes and an upregulation of the substance P system in a muscle overuse modelNeprilysin deficiency protects against fat-induced insulin secretory dysfunction by maintaining calcium influx.Cyclic expression of endothelin-converting enzyme-1 mediates the functional regulation of seminiferous tubule contraction.UK-414,495, a selective inhibitor of neutral endopeptidase, potentiates pelvic nerve-stimulated increases in female genital blood flow in the anaesthetized rabbitCD10 as a novel marker of therapeutic resistance and cancer stem cells in head and neck squamous cell carcinoma.Streptococcus parasanguis pepO encodes an endopeptidase with structure and activity similar to those of enzymes that modulate peptide receptor signaling in eukaryotic cells.Characterization of a streptococcal endopeptidase with homology to human endothelin-converting enzyme.Active site mutations change the cleavage specificity of neprilysin.Reduced fertility in male mice deficient in the zinc metallopeptidase NL1Amyloid beta-degrading cryptidases: insulin degrading enzyme, presequence peptidase, and neprilysin.Prevention of collagen-induced arthritis in mice by a polyphenolic fraction from green tea.An ethyl-nitrosourea-induced point mutation in phex causes exon skipping, x-linked hypophosphatemia, and rickets.Modulation of human colon tumor-stromal interactions by the endothelin system.Tumoral CD10 expression correlates with aggressive histology and prognosis in patients with malignant pleural mesothelioma.The wrickkened pathways of FGF23, MEPE and PHEX.FGF23, hypophosphatemia, and rickets: has phosphatonin been found?Tumoral CD10 expression correlates with high-grade histology and increases risk of recurrence in patients with stage I lung adenocarcinomaMedaka fish, Oryzias latipes, as a model for human obesity-related glomerulopathy.Neprilysin null mice develop exaggerated pulmonary vascular remodeling in response to chronic hypoxiaDistinct subcellular patterns of neprilysin protein and activity in the brains of Alzheimer's disease patients, transgenic mice and cultured human neuronal cells.The metabolic bone disease associated with the Hyp mutation is independent of osteoblastic HIF1α expression.Current therapeutic targets for the treatment of Alzheimer's disease.Tissue nonspecific alkaline phosphatase is activated via a two-step mechanism by zinc transport complexes in the early secretory pathwayAmyloid beta: structure, biology and structure-based therapeutic development.Palmitoylation of the three isoforms of human endothelin-converting enzyme-1The evolution of natriuretic peptide augmentation in management of heart failure and the role of sacubitril/valsartan.Mutagenesis of Glu403 to Cys in rabbit neutral endopeptidase-24.11 (neprilysin) creates a disulphide-linked homodimer: analogy with endothelin-converting enzyme.Novel activity of endothelin-converting enzyme: hydrolysis of bradykinin.Pharmacological hypothesis: Nitric oxide-induced inhibition of ADAM-17 activity as well as vesicle release can in turn prevent the production of soluble endothelin-converting enzyme.Big endothelin-1 but not endothelin-1 is present in the smooth muscle stroma of the prostate gland of the rat.Stromal CD10 expression in breast cancer correlates with tumor invasion and cancer stem cell phenotype.
P2860
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P2860
Mammalian membrane metallopeptidases: NEP, ECE, KELL, and PEX.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Mammalian membrane metallopeptidases: NEP, ECE, KELL, and PEX.
@en
type
label
Mammalian membrane metallopeptidases: NEP, ECE, KELL, and PEX.
@en
prefLabel
Mammalian membrane metallopeptidases: NEP, ECE, KELL, and PEX.
@en
P1433
P1476
Mammalian membrane metallopeptidases: NEP, ECE, KELL, and PEX.
@en
P2093
P304
P407
P577
1997-04-01T00:00:00Z