High frequencies of alpha-thalassaemia are the result of natural selection by malaria.
about
How malaria has affected the human genome and what human genetics can teach us about malariaPopulation genetics of malaria resistance in humansResistance to malaria in humans: the impact of strong, recent selectionThe effect of alpha+-thalassaemia on the incidence of malaria and other diseases in children living on the coast of KenyaEvolutionary and historical aspects of the burden of malaria.Genome-wide and fine-resolution association analysis of malaria in West AfricaGlobal distribution of the sickle cell gene and geographical confirmation of the malaria hypothesisTLR4 polymorphisms, infectious diseases, and evolutionary pressure during migration of modern humansEpistasis and the sensitivity of phenotypic screens for beta thalassaemiaOut-of-Africa, the peopling of continents and islands: tracing uniparental gene trees across the mapGenome wide analysis of inbred mouse lines identifies a locus containing Ppar-gamma as contributing to enhanced malaria survivalHaemoglobin C protects against clinical Plasmodium falciparum malariaGenetics of susceptibility to human infectious diseaseExploring the role of copy number variants in human adaptationDiversity of Plasmodium falciparum chloroquine resistance transporter (pfcrt) exon 2 haplotypes in the Pacific from 1959 to 1979The SLC4A1 gene is under differential selective pressure in primates infected by Plasmodium falciparum and related parasitesGenetic variation and adaptation in Africa: implications for human evolution and diseaseThe population genetics of structural variationIncreased microerythrocyte count in homozygous alpha(+)-thalassaemia contributes to protection against severe malarial anaemiaEvolutionary genetics of the human Rh blood group system.Heritability of the human infectious reservoir of malaria parasitesNon-deletion haemoglobin H disease in Papua New Guinea.Association between a common immunoglobulin heavy chain allele and rheumatic heart disease risk in Oceania.Positive replication and linkage disequilibrium mapping of the chromosome 21q22.1 malaria susceptibility locus.The functional impact of structural variation in humans.Regulatory and structural genes for lysozymes of mice.Copy number variation in human health, disease, and evolution.Science, medicine, and the future: susceptibility to infection.Single nucleotide polymorphisms and the future of genetic epidemiology.The thalassemia syndromes: molecular characterization in the Spanish population.Controlled somatic and germline copy number variation in the mouse modelProfile of Alec J. Jeffreys.Worldwide population distribution of the common LCE3C-LCE3B deletion associated with psoriasis and other autoimmune disordersProcesses of copy-number change in human DNA: the dynamics of {alpha}-globin gene deletion.Gamma chain abnormalities and gamma-globin gene rearrangements in newborn babies of various populations.A common 56-kilobase deletion in a primate-specific segmental duplication creates a novel butyrophilin-like protein.Genetic variability in response to infection: malaria and after.A human complement receptor 1 polymorphism that reduces Plasmodium falciparum rosetting confers protection against severe malaria.Alpha-globin gene markers identify genetic differences between Australian aborigines and MelanesiansGlobin genes are useful markers to identify genetic similarities between Fijians and Pacific Islanders from Polynesia and Melanesia
P2860
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P2860
High frequencies of alpha-thalassaemia are the result of natural selection by malaria.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
High frequencies of alpha-thalassaemia are the result of natural selection by malaria.
@en
type
label
High frequencies of alpha-thalassaemia are the result of natural selection by malaria.
@en
prefLabel
High frequencies of alpha-thalassaemia are the result of natural selection by malaria.
@en
P2093
P356
P1433
P1476
High frequencies of alpha-thalassaemia are the result of natural selection by malaria.
@en
P2093
Bana-Koiri J
Oppenheimer SJ
Serjeantson SW
P2888
P304
P356
10.1038/321744A0
P407
P577
1986-06-01T00:00:00Z
P6179
1006612157