Differential stabilities of alternative exon-skipped rod motifs of dystrophin.
about
Missense mutation Lys18Asn in dystrophin that triggers X-linked dilated cardiomyopathy decreases protein stability, increases protein unfolding, and perturbs protein structure, but does not affect protein function.The Dystrophin Complex: Structure, Function, and Implications for TherapyExon-skipped dystrophins for treatment of Duchenne muscular dystrophy: mass spectrometry mapping of most exons and cooperative domain designs based on single molecule mechanicsDisease-causing missense mutations in actin binding domain 1 of dystrophin induce thermodynamic instability and protein aggregation.Internal deletion compromises the stability of dystrophinClinical phenotypes as predictors of the outcome of skipping around DMD exon 45.In vitro stability of therapeutically relevant, internally truncated dystrophins.Microdystrophin ameliorates muscular dystrophy in the canine model of duchenne muscular dystrophyAAV-directed muscular dystrophy gene therapy.Exon skipping for nonsense mutations in Duchenne muscular dystrophy: too many mutations, too few patients?Engineering multiple U7snRNA constructs to induce single and multiexon-skipping for Duchenne muscular dystrophy.Thermodynamic stability, unfolding kinetics, and aggregation of the N-terminal actin-binding domains of utrophin and dystrophin.Dystrophin levels and clinical severity in Becker muscular dystrophy patients.
P2860
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P2860
Differential stabilities of alternative exon-skipped rod motifs of dystrophin.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Differential stabilities of alternative exon-skipped rod motifs of dystrophin.
@en
type
label
Differential stabilities of alternative exon-skipped rod motifs of dystrophin.
@en
prefLabel
Differential stabilities of alternative exon-skipped rod motifs of dystrophin.
@en
P2093
P2860
P1476
Differential stabilities of alternative exon-skipped rod motifs of dystrophin.
@en
P2093
Ahmed Mirza
Chris Ruszczak
Nick Menhart
P2860
P304
P356
10.1016/J.BBAPAP.2009.02.016
P577
2009-03-12T00:00:00Z