about
Structural and functional characterization of Mycobacterium tuberculosis CmtR, a PbII/CdII-sensing SmtB/ArsR metalloregulatory repressorZn(II) and Hg(II) binding to a designed peptide that accommodates different coordination geometries.The application of (199)Hg NMR and (199m)Hg perturbed angular correlation (PAC) spectroscopy to define the biological chemistry of Hg(II): a case study with designed two- and three-stranded coiled coils.Zinc ion-induced domain organization in metallo-beta-lactamases: a flexible "zinc arm" for rapid metal ion transfer?d-Cysteine Ligands Control Metal Geometries within De Novo Designed Three-Stranded Coiled Coils.Reparameterization of all-atom dipalmitoylphosphatidylcholine lipid parameters enables simulation of fluid bilayers at zero tension.Direct Observation of Nanosecond Water Exchange Dynamics at a Protein Metal SiteAmyloid-β and α-Synuclein Decrease the Level of Metal-Catalyzed Reactive Oxygen Species by Radical Scavenging and Redox Silencing.Using diastereopeptides to control metal ion coordination in proteinsA Cu(I)-sensing ArsR family metal sensor protein with a relaxed metal selectivity profile.Design of thiolate rich metal binding sites within a peptidic framework.Probing the coordination environment of the human copper chaperone HAH1: characterization of Hg(II)-bridged homodimeric species in solution.Variable primary coordination environments of Cd(II) binding to three helix bundles provide a pathway for rapid metal exchange.Nanosecond Dynamics at Protein Metal Sites: An Application of Perturbed Angular Correlation (PAC) of γ-Rays Spectroscopy.Catalytic role of the metal ion in the metallo-beta-lactamase GOB.Metal ion mediated transition from random coil to β-sheet and aggregation of Bri2-23, a natural inhibitor of Aβ aggregation.Fully relativistic coupled cluster and DFT study of electric field gradients at Hg in 199Hg compounds.Dynamics of mononuclear cadmium beta-lactamase revealed by the combination of NMR and PAC spectroscopy.Comparison of the binding of cadmium(II), mercury(II), and arsenic(III) to the de novo designed peptides TRI L12C and TRI L16C.Binding of D- and L-captopril inhibitors to metallo-beta-lactamase studied by polarizable molecular mechanics and quantum mechanics.Evaluation of carbohydrate molecular mechanical force fields by quantum mechanical calculations.Docking and scoring of metallo-beta-lactamases inhibitors.Application of 204mPb perturbed angular correlation of γ-rays spectroscopy in coordination chemistry.Structural adaptability of zinc binding sites: different structures in partially, fully, and heavy-metal loaded states.Incorporation of second coordination sphere D-amino acids alters Cd(II) geometries in designed thiolate-rich proteins.Aggregation-Prone Amyloid-β⋅Cu(II) Species Formed on the Millisecond Timescale under Mildly Acidic Conditions.Structure and absolute configuration of nyasol and hinokiresinol via synthesis and vibrational circular dichroism spectroscopy.Billion-fold enhancement in sensitivity of nuclear magnetic resonance spectroscopy for magnesium ions in solution.New leads of metallo-beta-lactamase inhibitors from structure-based pharmacophore design.The Pathogenic A2V Mutant Exhibits Distinct Aggregation Kinetics, Metal Site Structure, and Metal Exchange of the Cu2+ -Aβ Complex.Rapid exchange of metal between Zn(7)-metallothionein-3 and amyloid-β peptide promotes amyloid-related structural changes.Direct determination of absolute configuration of methyl-substituted phenyloxiranes: combined experimental and theoretical approach.Electric field gradients in Hg compounds: molecular orbital (MO) analysis and comparison of 4-component and 2-component (ZORA) methods.Interaction and coordination geometries for Ag(I) in the two metal sites of hemocyanin.Plastocyanin binding to photosystem I as a function of the charge state of the metal ion: effect of metal site conformation.The protein conformation of Cd-substituted horse liver alcohol dehydrogenase and its metal-site coordination geometry in binary and ternary inhibitor complexes.Cd-substituted horse liver alcohol dehydrogenase: catalytic site metal coordination geometry and protein conformation.Fast cadmium inhibition of photosynthesis in cyanobacteria in vivo and in vitro studies using perturbed angular correlation of gamma-rays.Specificity of the Metalloregulator CueR for Monovalent Metal Ions: Possible Functional Role of a Coordinated Thiol?Direct observation of Mg complexes in ionic liquid solutions by Mg β-NMR spectroscopy
P50
Q28486630-38E75AD7-9659-4FAB-BCEC-338B9DE3E2E8Q30964852-55D08B4B-EA95-4BD4-A334-04FEC7B63571Q31134248-8906FAE7-BAE6-46F9-8D8D-54C68C53FAABQ33435167-022F7774-140A-46DC-813E-D144E423F1C3Q33919738-C1B8EAAE-28EC-4ABC-968A-96F5A6F6AC8AQ35812265-EDF32C52-0235-42C7-BCED-F79983E5EE06Q36223944-215411F4-8B6D-40C9-8E4C-EB09F6986023Q36787715-7D944F2C-46C5-4DDA-A6DA-A5C6755301EBQ36954896-EEA417BD-FF16-4002-AFC0-A13BF0C452DEQ37008124-8573A3D0-233A-4D9C-80C9-24C4FFF49AB8Q37115356-C266A567-309F-4EA1-9020-61CFF01144E5Q37270528-656CC9CE-2218-4E71-9892-3108F9BD8B70Q37596622-48D51269-1328-4493-8CB2-51712E55A6F3Q38612885-01D3222B-1A40-494D-BD3C-42D69B535F5BQ39541312-E6F3C738-C30D-42E9-91AC-76D3BA393BE4Q41508703-157A639C-ED75-494C-A40E-C9E8AE30B426Q43545912-5071F0FE-03A9-4C88-AA91-756763450C6DQ43768679-4766F82D-A25C-4D46-9A3F-47D3F852093BQ44048743-D76C58D0-44E2-40E1-8E93-4B5A7E6EEAD6Q44124582-F4304D48-287C-4CD8-AED0-97C0CCDB39BBQ44792756-17CD8461-5B88-46B9-9EEE-1D6A1DB1E094Q45162110-326F2ACE-EB29-4D57-A10F-863AD3DB1428Q45793720-8BBD75C2-3E01-4984-B445-2F0A3FAF43DEQ45938064-0FCD6654-6663-47D7-842A-D43CE5668700Q46245486-690A304B-95BB-4D6D-AE23-0F077CD368D8Q46726802-6AAC4A15-C6E3-4A83-BA45-36385DD0F3DFQ46821278-1F934073-731B-44D9-8D19-C39FB788F06DQ46827105-00A48017-4FAD-476C-A1B7-C15F363FE191Q46868940-8560E26F-0B12-4E03-94F8-E224FE82E0C9Q47942319-90A32FE3-2F97-42B1-AE1F-ECB4424F0E4BQ50335545-65E20E9F-9ED1-4D31-A674-57A008603F7AQ50722272-D16682E6-D8CC-45DB-9716-40028FE21C9DQ51304872-E2E26895-4909-4A0A-AD5E-425149F20A0DQ52081149-31777B8E-6EDD-4AA6-A1E9-2E160FE255B8Q52205765-AD70F393-F34B-4490-95E0-4C0F2C1139C7Q52293795-5D5F86F0-7B0D-4AF9-8D42-11204DD44C5FQ52341250-6EAB1327-48EF-43D8-BB4C-8BB0AC6FFC7BQ53808116-15C5977A-8EAC-4F88-BADD-0E1338D18A8CQ54256661-62270E41-F5EC-44DD-BF49-71F8061C37A8Q57035869-1F5680B0-1D6A-4A59-A72B-E5A1F69E568D
P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Lars Hemmingsen
@ast
Lars Hemmingsen
@en
Lars Hemmingsen
@es
Lars Hemmingsen
@sl
type
label
Lars Hemmingsen
@ast
Lars Hemmingsen
@en
Lars Hemmingsen
@es
Lars Hemmingsen
@sl
prefLabel
Lars Hemmingsen
@ast
Lars Hemmingsen
@en
Lars Hemmingsen
@es
Lars Hemmingsen
@sl
P1053
A-6780-2015
P106
P21
P31
P3829
P496
0000-0002-1823-3035