Neu differentiation factor (heregulin) induces expression of intercellular adhesion molecule 1: implications for mammary tumors.
about
The N-terminal 24 amino acids of the p55 gamma regulatory subunit of phosphoinositide 3-kinase binds Rb and induces cell cycle arrestInteraction of the PA2G4 (EBP1) protein with ErbB-3 and regulation of this binding by heregulinMedullary carcinoma is associated with expression of intercellular adhesion molecule-1. Implication to its morphology and its clinical behaviorEGFR/HER-targeted therapeutics in ovarian cancerErbB tyrosine kinases and the two neuregulin families constitute a ligand-receptor network.Synergistic down-regulation of receptor tyrosine kinases by combinations of mAbs: implications for cancer immunotherapy.Her4 mediates ligand-dependent antiproliferative and differentiation responses in human breast cancer cells.Antisense DNA downregulation of the ERBB2 oncogene measured by a flow cytometric assay.The HER4 cytoplasmic domain, but not its C terminus, inhibits mammary cell proliferation.The EGF receptor family--multiple roles in proliferation, differentiation, and neoplasia with an emphasis on HER4Type 1 receptor tyrosine kinases are differentially phosphorylated in mammary carcinoma and differentially associated with steroid receptors.Brain neurons and glial cells express Neu differentiation factor/heregulin: a survival factor for astrocytes.Nuclear functions and subcellular trafficking mechanisms of the epidermal growth factor receptor familySequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland.ErbB2 is necessary for induction of carcinoma cell invasion by ErbB family receptor tyrosine kinases.Down-regulation of α-L-fucosidase 1 expression confers inferior survival for triple-negative breast cancer patients by modulating the glycosylation status of the tumor cell surfaceErbB2 expression increases the spectrum and potency of ligand-mediated signal transduction through ErbB4.Neu differentiation factor activation of ErbB-3 and ErbB-4 is cell specific and displays a differential requirement for ErbB-2.Sp1 binding plays a critical role in Erb-B2- and v-ras-mediated downregulation of alpha2-integrin expression in human mammary epithelial cells.Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patientsProtein phosphatase Mg2+/Mn2+ dependent 1F promotes smoking-induced breast cancer by inactivating phosphorylated-p53-induced signals.Inhibition of heregulin mediated MCF-7 breast cancer cell growth by the ErbB3 binding protein EBP1.Single-chain antibody-mediated intracellular retention of ErbB-2 impairs Neu differentiation factor and epidermal growth factor signaling.Reconstitution of mammary gland development in vitro: requirement of c-met and c-erbB2 signaling for branching and alveolar morphogenesis.
P2860
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P2860
Neu differentiation factor (heregulin) induces expression of intercellular adhesion molecule 1: implications for mammary tumors.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Neu differentiation factor (he ...... plications for mammary tumors.
@en
type
label
Neu differentiation factor (he ...... plications for mammary tumors.
@en
prefLabel
Neu differentiation factor (he ...... plications for mammary tumors.
@en
P2093
P1433
P1476
Neu differentiation factor (he ...... plications for mammary tumors.
@en
P2093
Ben-Baruch N
Farbstein H
Stancovski I
Zelnick CR
P304
P407
P50
P577
1993-11-01T00:00:00Z