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The NH2 terminus of titin spans the Z-disc: its interaction with a novel 19-kD ligand (T-cap) is required for sarcomeric integrityObscurin, a giant sarcomeric Rho guanine nucleotide exchange factor protein involved in sarcomere assemblyRole of titin in vertebrate striated muscleMuscle-specific RING finger-1 interacts with titin to regulate sarcomeric M-line and thick filament structure and may have nuclear functions via its interaction with glucocorticoid modulatory element binding protein-1Mechanoenzymatics of titin kinase.Molecular structure of the sarcomeric Z-disk: two types of titin interactions lead to an asymmetrical sorting of alpha-actinin.Human autoantibodies reveal titin as a chromosomal proteinPhosphorylation switches specific for the cardiac isoform of myosin binding protein-C: a modulator of cardiac contraction?Tibial muscular dystrophy is a titinopathy caused by mutations in TTN, the gene encoding the giant skeletal-muscle protein titinLocalization of the binding site of the C-terminal domain of cardiac myosin-binding protein-C on the myosin rodCellular titin localization in stress fibers and interaction with myosin II filaments in vitroAssembly of the giant protein projectin during myofibrillogenesis in Drosophila indirect flight musclesTitin kinase is an inactive pseudokinase scaffold that supports MuRF1 recruitment to the sarcomeric M-lineGiant protein kinases: domain interactions and structural basis of autoregulationDominant negative effect of cytoplasmic actin isoproteins on cardiomyocyte cytoarchitecture and functionInhibition of CapZ during myofibrillogenesis alters assembly of actin filamentsInvertebrate connectin spans as much as 3.5 microm in the giant sarcomeres of crayfish claw muscle.Mechanical dynamics in live cells and fluorescence-based force/tension sensorsThe Caenorhabditis elegans gene unc-89, required fpr muscle M-line assembly, encodes a giant modular protein composed of Ig and signal transduction domainsThree-dimensional structure of vertebrate cardiac muscle myosin filaments.Modeling AFM-induced PEVK extension and the reversible unfolding of Ig/FNIII domains in single and multiple titin moleculesA kinetic molecular model of the reversible unfolding and refolding of titin under force extension.The structure of isolated cardiac Myosin thick filaments from cardiac Myosin binding protein-C knockout mice.Expression of a novel myosin light chain kinase in embryonic tissues and cultured cells.Myosin binding protein-C slow: an intricate subfamily of proteins.Increased Postnatal Cardiac Hyperplasia Precedes Cardiomyocyte Hypertrophy in a Model of Hypertrophic Cardiomyopathy.Actin-titin interaction in cardiac myofibrils: probing a physiological role.Passive tension and stiffness of vertebrate skeletal and insect flight muscles: the contribution of weak cross-bridges and elastic filaments.The effect of genetically expressed cardiac titin fragments on in vitro actin motility.Passive tension in cardiac muscle: contribution of collagen, titin, microtubules, and intermediate filamentsOrder statistics theory of unfolding of multimeric proteins.The structure of the sarcomeric M band: localization of defined domains of myomesin, M-protein, and the 250-kD carboxy-terminal region of titin by immunoelectron microscopy.Deleting titin's I-band/A-band junction reveals critical roles for titin in biomechanical sensing and cardiac function.DIM-1, a novel immunoglobulin superfamily protein in Caenorhabditis elegans, is necessary for maintaining bodywall muscle integrityExome sequencing identifies titin mutations causing hereditary myopathy with early respiratory failure (HMERF) in families of diverse ethnic originsThe giant protein titin: a regulatory node that integrates myocyte signaling pathways.Muscle giants: molecular scaffolds in sarcomerogenesis.Titin visualization in real time reveals an unexpected level of mobility within and between sarcomerescAMP-dependent phosphorylation of Aplysia twitchin may mediate modulation of muscle contractions by neuropeptide cotransmitters.Reversible unfolding of fibronectin type III and immunoglobulin domains provides the structural basis for stretch and elasticity of titin and fibronectin
P2860
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P2860
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Towards a molecular understanding of titin.
@en
type
label
Towards a molecular understanding of titin.
@en
prefLabel
Towards a molecular understanding of titin.
@en
P2093
P2860
P1433
P1476
Towards a molecular understanding of titin.
@en
P2093
P2860
P304
P407
P577
1992-05-01T00:00:00Z