about
Intracellular CXCR4⁺ cell targeting with T22-empowered protein-only nanoparticles.Functional inclusion bodies produced in the yeast Pichia pastoris.Engineered biological entities for drug delivery and gene therapy protein nanoparticles.Dialysis: a characterization method of aggregation tendency.BBB-targeting, protein-based nanomedicines for drug and nucleic acid delivery to the CNS.Structural and functional features of self-assembling protein nanoparticles produced in endotoxin-free Escherichia coli.Intrinsic functional and architectonic heterogeneity of tumor-targeted protein nanoparticles.Intracellular targeting of CD44+ cells with self-assembling, protein only nanoparticles.A nanostructured bacterial bioscaffold for the sustained bottom-up delivery of protein drugs.CXCR4(+)-targeted protein nanoparticles produced in the food-grade bacterium Lactococcus lactis.Internalization and kinetics of nuclear migration of protein-only, arginine-rich nanoparticles.Protein-only, antimicrobial peptide-containing recombinant nanoparticles with inherent built-in antibacterial activity.Bottom-Up Instructive Quality Control in the Biofabrication of Smart Protein Materials.Bacterial mimetics of endocrine secretory granules as immobilized in vivo depots for functional protein drugs.Rehosting of bacterial chaperones for high-quality protein production.Towards protein-based viral mimetics for cancer therapies.In vivo architectonic stability of fully de novo designed protein-only nanoparticles.Sheltering DNA in self-organizing, protein-only nano-shells as artificial viruses for gene delivery.Improved performance of protein-based recombinant gene therapy vehicles by tuning downstream procedures.Protein nanodisk assembling and intracellular trafficking powered by an arginine-rich (R9) peptide.Nanoparticulate architecture of protein-based artificial viruses is supported by protein-DNA interactions.Conformational and functional variants of CD44-targeted protein nanoparticles bio-produced in bacteria.Rational engineering of single-chain polypeptides into protein-only, BBB-targeted nanoparticles.Topographically targeted osteogenesis of mesenchymal stem cells stimulated by inclusion bodies attached to polycaprolactone surfaces.Protein-Based Therapeutic Killing for Cancer Therapies.Engineering multifunctional protein nanoparticles by in vitro disassembling and reassembling of heterologous building blocks.Intracellular trafficking of a dynein-based nanoparticle designed for gene delivery.The fusogenic peptide HA2 impairs selectivity of CXCR4-targeted protein nanoparticles.Protein nanoparticles are nontoxic, tuneable cell stressors.Self-assembling toxin-based nanoparticles as self-delivered antitumoral drugs.Engineering tumor cell targeting in nanoscale amyloidal materials.Protein aggregation and soluble aggregate formation screened by a fast microdialysis assay.Release of targeted protein nanoparticles from functional bacterial amyloids: A death star-like approach.Strategies for the production of difficult-to-express full-length eukaryotic proteins using microbial cell factories: production of human alpha-galactosidase A.Switching cell penetrating and CXCR4-binding activities of nanoscale-organized arginine-rich peptides.Assembly of histidine-rich protein materials controlled through divalent cationsRGD-based cell ligands for cell-targeted drug delivery act as potent trophic factorsSelective depletion of metastatic stem cells as therapy for human colorectal cancerConformational Conversion during Controlled Oligomerization into Nonamylogenic Protein NanoparticlesSelective CXCR4+ Cancer Cell Targeting and Potent Antineoplastic Effect by a Nanostructured Version of Recombinant Ricin
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P50
description
Spaans onderzoeker
@nl
Spanish researcher
@en
investigador espanhol
@pt
taighdeoir Spáinneach
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name
Ugutz Unzueta
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Ugutz Unzueta
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Ugutz Unzueta
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Ugutz Unzueta
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Ugutz Unzueta
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Ugutz Unzueta
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Ugutz Unzueta
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type
label
Ugutz Unzueta
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Ugutz Unzueta
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Ugutz Unzueta
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Ugutz Unzueta
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Ugutz Unzueta
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Ugutz Unzueta
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Ugutz Unzueta
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altLabel
Unzueta U.
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prefLabel
Ugutz Unzueta
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Ugutz Unzueta
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Ugutz Unzueta
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Ugutz Unzueta
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Ugutz Unzueta
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Ugutz Unzueta
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Ugutz Unzueta
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P214
P1053
C-2521-2017
P106
P1153
35801390400
P1477
Ugutz Unzueta Elorza
@eu
P214
P27
P31
P3829
P496
0000-0001-5119-2266
P7859
viaf-316753840