Extinction of Oct-3/4 gene expression in embryonal carcinoma x fibroblast somatic cell hybrids is accompanied by changes in the methylation status, chromatin structure, and transcriptional activity of the Oct-3/4 upstream region
about
Sequential DNA methylation of the Nanog and Oct-4 upstream regions in human NT2 cells during neuronal differentiationSynergistic function of DNA methyltransferases Dnmt3a and Dnmt3b in the methylation of Oct4 and NanogRegulation of the Oct-4 gene by nuclear receptorsA dynamic balance between ARP-1/COUP-TFII, EAR-3/COUP-TFI, and retinoic acid receptor:retinoid X receptor heterodimers regulates Oct-3/4 expression in embryonal carcinoma cellsDistinct epigenomic landscapes of pluripotent and lineage-committed human cells.Rex-1, a gene encoding a transcription factor expressed in the early embryo, is regulated via Oct-3/4 and Oct-6 binding to an octamer site and a novel protein, Rox-1, binding to an adjacent site.Transcriptional silencing and translational control: key features of early germline development.Retinoic acid-mediated down-regulation of Oct3/4 coincides with the loss of promoter occupancy in vivo.Phosphorylation regulates human OCT4.Histone code modifications on pluripotential nuclei of reprogrammed somatic cells.Retinoic acid represses Oct-3/4 gene expression through several retinoic acid-responsive elements located in the promoter-enhancer region.Testicular Germ Cell Tumors: A Paradigm for the Successful Treatment of Solid Tumor Stem Cells.Micro-RNA mediated regulation of proliferation, self-renewal and differentiation of mammalian stem cellsLocus- and cell type-specific epigenetic switching during cellular differentiation in mammalsDNA methylation dynamics in health and disease.Multi-layered global gene regulation in mouse embryonic stem cells.Expression analysis of BORIS during pluripotent, differentiated, cancerous, and non-cancerous cell states.Mechanisms of pluripotency maintenance in mouse embryonic stem cells.Comparative epigenetic analysis of Oct4 regulatory region in RA-induced differentiated NT2 cells under adherent and non-adherent culture conditions.Differential recruitment of methyl CpG-binding domain factors and DNA methyltransferases by the orphan receptor germ cell nuclear factor initiates the repression and silencing of Oct4.Hepatocyte nuclear factor-4 prevents silencing of hepatocyte nuclear factor-1 expression in hepatoma x fibroblast cell hybrids.Epigenetic deregulation of the human Oct4 promoter in mouse cells.Differential recruitment of methylated CpG binding domains by the orphan receptor GCNF initiates the repression and silencing of Oct4 expression.Characterization of putative cis-regulatory elements that control the transcriptional activity of the human Oct4 promoter.Hybrid cell extinction and re-expression of Oct-3 function correlates with differentiation potential.Selective ablation of differentiated cells permits isolation of embryonic stem cell lines from murine embryos with a non-permissive genetic background.A role for nuclear NF-kappaB in B-cell-specific demethylation of the Igkappa locus.A unique developmental pattern of Oct-3/4 DNA methylation is controlled by a cis-demodification element.Autoregulatory loop and retinoic acid repression regulate pou2/pou5f1 gene expression in the zebrafish embryonic brain.Expression of Pou3f3/Brn-1 and its genomic methylation in developing auditory epithelium.Abnormal DNA methylation of the Oct-4 enhancer region in cloned mouse embryos.Regulation of Oct-4 gene expression during differentiation of EC cells.Developmental changes in methylation of spermatogenesis-specific genes include reprogramming in the epididymis.
P2860
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P2860
Extinction of Oct-3/4 gene expression in embryonal carcinoma x fibroblast somatic cell hybrids is accompanied by changes in the methylation status, chromatin structure, and transcriptional activity of the Oct-3/4 upstream region
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Extinction of Oct-3/4 gene exp ...... of the Oct-3/4 upstream region
@en
type
label
Extinction of Oct-3/4 gene exp ...... of the Oct-3/4 upstream region
@en
prefLabel
Extinction of Oct-3/4 gene exp ...... of the Oct-3/4 upstream region
@en
P2093
P2860
P356
P1476
Extinction of Oct-3/4 gene exp ...... of the Oct-3/4 upstream region
@en
P2093
P2860
P304
P356
10.1128/MCB.13.2.891
P407
P577
1993-02-01T00:00:00Z