The CRISPR/Cas adaptive immune system of Pseudomonas aeruginosa mediates resistance to naturally occurring and engineered phages
about
Alternative roles for CRISPR/Cas systems in bacterial pathogenesisGenomics and genetics of Sulfolobus islandicus LAL14/1, a model hyperthermophilic archaeonProtospacer recognition motifs: mixed identities and functional diversityEvolutionary Ecology of Prokaryotic Immune MechanismsBiogenesis pathways of RNA guides in archaeal and bacterial CRISPR-Cas adaptive immunityMolecular mechanisms of CRISPR-mediated microbial immunityCRISPR-Cas systems and RNA-guided interferenceCRISPR-mediated defense mechanisms in the hyperthermophilic archaeal genus SulfolobusSynthetic biology to access and expand nature's chemical diversityBacteriophages and phage-derived proteins--application approachesHolding a grudge: persisting anti-phage CRISPR immunity in multiple human gut microbiomes.Cas1 and the Csy complex are opposing regulators of Cas2/3 nuclease activity.Bacteriophage genes that inactivate the CRISPR/Cas bacterial immune system.Dealing with the evolutionary downside of CRISPR immunity: bacteria and beneficial plasmids.CRISPR-Cas systems: beyond adaptive immunity.Multiple mechanisms for CRISPR-Cas inhibition by anti-CRISPR proteinsAbundant and diverse clustered regularly interspaced short palindromic repeat spacers in Clostridium difficile strains and prophages target multiple phage types within this pathogenFunction and regulation of clustered regularly interspaced short palindromic repeats (CRISPR) / CRISPR associated (Cas) systems.The tracrRNA and Cas9 families of type II CRISPR-Cas immunity systems.Target motifs affecting natural immunity by a constitutive CRISPR-Cas system in Escherichia coli.In defense of phage: viral suppressors of CRISPR-mediated adaptive immunity in bacteria.Cytotoxic chromosomal targeting by CRISPR/Cas systems can reshape bacterial genomes and expel or remodel pathogenicity islandsThe susceptibility of Pseudomonas aeruginosa strains from cystic fibrosis patients to bacteriophages.The resistome of Pseudomonas aeruginosa in relationship to phenotypic susceptibilityType I-E CRISPR-cas systems discriminate target from non-target DNA through base pairing-independent PAM recognition.CRISPR-Cas immunity against phages: its effects on the evolution and survival of bacterial pathogens.Transcriptional regulator-mediated activation of adaptation genes triggers CRISPR de novo spacer acquisition.Role of the Streptococcus mutans CRISPR-Cas systems in immunity and cell physiology.Mechanism of foreign DNA recognition by a CRISPR RNA-guided surveillance complex from Pseudomonas aeruginosaDegenerate target sites mediate rapid primed CRISPR adaptation.I can see CRISPR now, even when phage are gone: a view on alternative CRISPR-Cas functions from the prokaryotic envelope.Comparative genomics reveals diversified CRISPR-Cas systems of globally distributed Microcystis aeruginosa, a freshwater bloom-forming cyanobacterium.Clustered Regularly Interspaced Short Palindromic Repeat-Dependent, Biofilm-Specific Death of Pseudomonas aeruginosa Mediated by Increased Expression of Phage-Related Genes.Investigation of a Large Collection of Pseudomonas aeruginosa Bacteriophages Collected from a Single Environmental Source in Abidjan, Côte d'Ivoire.Phylogenetic Distribution of CRISPR-Cas Systems in Antibiotic-Resistant Pseudomonas aeruginosa.DNA targeting by the type I-G and type I-A CRISPR-Cas systems of Pyrococcus furiosus.Foreign DNA acquisition by the I-F CRISPR-Cas system requires all components of the interference machinery.A genetic approach to the development of new therapeutic phages to fight pseudomonas aeruginosa in wound infections.The CRISPR-associated gene cas2 of Legionella pneumophila is required for intracellular infection of amoebae.CRISPRTarget: bioinformatic prediction and analysis of crRNA targets.
P2860
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P2860
The CRISPR/Cas adaptive immune system of Pseudomonas aeruginosa mediates resistance to naturally occurring and engineered phages
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
The CRISPR/Cas adaptive immune ...... ccurring and engineered phages
@en
type
label
The CRISPR/Cas adaptive immune ...... ccurring and engineered phages
@en
prefLabel
The CRISPR/Cas adaptive immune ...... ccurring and engineered phages
@en
P2093
P2860
P356
P1476
The CRISPR/Cas adaptive immune ...... ccurring and engineered phages
@en
P2093
Alan R Davidson
Gary E Heussler
George A O'Toole
Joe Bondy-Denomy
Kyle C Cady
P2860
P304
P356
10.1128/JB.01184-12
P577
2012-08-10T00:00:00Z