about
Modeling metabolic networks in C. glutamicum: a comparison of rate laws in combination with various parameter optimization strategiesCurrent state and challenges for dynamic metabolic modelingStimulation, monitoring, and analysis of pathway dynamics by metabolic profiling in the aromatic amino acid pathwayAutomation of a Nile red staining assay enables high throughput quantification of microalgal lipid productionStandard reporting requirements for biological samples in metabolomics experiments: microbial and in vitro biology experiments.Polyketide proofreading by an acyltransferase-like enzyme.Use of a Sec signal peptide library from Bacillus subtilis for the optimization of cutinase secretion in Corynebacterium glutamicum.Fast and reliable strain characterization of Streptomyces lividans through micro-scale cultivation.A framework for accelerated phototrophic bioprocess development: integration of parallelized microscale cultivation, laboratory automation and Kriging-assisted experimental design.Application of metabolic engineering for the biotechnological production of L-valine.Comparative 13C metabolic flux analysis of pyruvate dehydrogenase complex-deficient, L-valine-producing Corynebacterium glutamicum.Metabolic profile of 1,5-diaminopentane producing Corynebacterium glutamicum under scale-down conditions: Blueprint for robustness to bioreactor inhomogeneities.Bioprocess automation on a Mini Pilot Plant enables fast quantitative microbial phenotyping.Metabolic and transcriptional response to cofactor perturbations in Escherichia coli.Distinct purinergic signaling pathways in prepubescent mouse spermatogonia.(13)C Tracers for Glucose Degrading Pathway Discrimination in Gluconobacter oxydans 621H.Process inhomogeneity leads to rapid side product turnover in cultivation of Corynebacterium glutamicumMetabolic impact of increased NADH availability in Saccharomyces cerevisiaeAn automated workflow for enhancing microbial bioprocess optimization on a novel microbioreactor platform.L-valine production with pyruvate dehydrogenase complex-deficient Corynebacterium glutamicum.A 2-oxoacid dehydrogenase complex of Haloferax volcanii is essential for growth on isoleucine but not on other branched-chain amino acids.Studies on substrate utilisation in L-valine-producing Corynebacterium glutamicum strains deficient in pyruvate dehydrogenase complex.Importance of NADPH supply for improved L-valine formation in Corynebacterium glutamicum.Analysing overexpression of L-valine biosynthesis genes in pyruvate-dehydrogenase-deficient Corynebacterium glutamicum.Application of immobilized bovine enterokinase in repetitive fusion protein cleavage for the production of mucin 1.The identification of enzyme targets for the optimization of a valine producing Corynebacterium glutamicum strain using a kinetic model.Conversion of Corynebacterium glutamicum from an aerobic respiring to an aerobic fermenting bacterium by inactivation of the respiratory chain.In vivo assessment by Mach-Zehnder double-beam interferometry of the invasive force exerted by the Asian soybean rust fungus (Phakopsora pachyrhizi).Metabolomics for biotransformations: Intracellular redox cofactor analysis and enzyme kinetics offer insight into whole cell processes.Metabolic impact of redox cofactor perturbations in Saccharomyces cerevisiae.Differential transcriptomic analysis reveals hidden light response in Streptomyces lividans.Comparative evaluation of phototrophic microtiter plate cultivation against laboratory-scale photobioreactors.Design and validation of a parallelized micro-photobioreactor enabling phototrophic bioprocess development at elevated throughput.Analysis of amino acids without derivatization in barley extracts by LC-MS-MS.Corynebacterium glutamicum tailored for high-yield L-valine production.Influence of L-isoleucine and pantothenate auxotrophy for L-valine formation in Corynebacterium glutamicum revisited by metabolome analyses.Rapid assessment of oxygen transfer impact for Corynebacterium glutamicum.Automated growth rate determination in high-throughput microbioreactor systems.pH fluctuations imperil the robustness of C. glutamicum to short term oxygen limitation.Effect of pyruvate dehydrogenase complex deficiency on L-lysine production with Corynebacterium glutamicum.
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hulumtues
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Marco Oldiges
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Marco Oldiges
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Marco Oldiges
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