Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis.
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Pathophysiology of systemic sclerosisMesothelial cells in tissue repair and fibrosisMolecular Interactions between NR4A Orphan Nuclear Receptors and NF-κB Are Required for Appropriate Inflammatory Responses and Immune Cell Homeostasis.Nur77 prevents excessive osteoclastogenesis by inducing ubiquitin ligase Cbl-b to mediate NFATc1 self-limitation.Nur77-deficiency in bone marrow-derived macrophages modulates inflammatory responses, extracellular matrix homeostasis, phagocytosis and toleranceTreatment of cholestatic fibrosis by altering gene expression of Cthrc1: Implications for autoimmune and non-autoimmune liver disease.Transcription factor Nr4a1 couples sympathetic and inflammatory cues in CNS-recruited macrophages to limit neuroinflammation.Knockdown of lncRNA-ATB suppresses autocrine secretion of TGF-β2 by targeting ZNF217 via miR-200c in keloid fibroblasts.Pan PPAR agonist IVA337 is effective in prevention and treatment of experimental skin fibrosis.Dissecting fibrosis: therapeutic insights from the small-molecule toolbox.Unfolding the pathogenesis of scleroderma through genomics and epigenomics.Liver fibrosis in 2015: Crucial steps towards an effective treatment.Stem Cell-Mediated Paracrine Signaling Alters Fibroplasia in Human Vocal Fold Fibroblasts in Vitro.Epigenetic regulation of cardiac fibrosis.NR4A1 is an endogenous inhibitor of vocal fold fibrosis.TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology.Nuclear receptor function in skin health and disease: therapeutic opportunities in the orphan and adopted receptor classes.Treatment of systemic sclerosis: is there any hope for the future?Injectable nanofibrous spongy microspheres for NR4A1 plasmid DNA transfection to reverse fibrotic degeneration and support disc regeneration.Anti-fibrotic effects of valproic acid: role of HDAC inhibition and associated mechanisms.Review: Frontiers of Antifibrotic Therapy in Systemic Sclerosis.NR4A Receptors Differentially Regulate NF-κB Signaling in Myeloid Cells.Nuclear receptor 4A (NR4A) family - orphans no more.Composition of TWIST1 dimers regulates fibroblast activation and tissue fibrosis.Antiviral properties of resveratrol against pseudorabies virus are associated with the inhibition of IκB kinase activation.Hepatic stellate cells as key target in liver fibrosis.Screening of candidate genes in fibroblasts derived from patients with Dupuytren's contracture using bioinformatics analysis.Nintedanib inhibits fibroblast activation and ameliorates fibrosis in preclinical models of systemic sclerosis.Gender differences in fibrosis remodeling in patients with long-standing persistent atrial fibrillation.Orphan nuclear receptor NR4A2 inhibits hepatic stellate cell proliferation through MAPK pathway in liver fibrosisActivation of STAT3 integrates common profibrotic pathways to promote fibroblast activation and tissue fibrosis.Plasminogen Activator Inhibitor Type I Controls Cardiomyocyte Transforming Growth Factor-β and Cardiac Fibrosis.TGFB1 is secreted through an unconventional pathway dependent on the autophagic machinery and cytoskeletal regulators.Identification of a Multipotent Progenitor Population in the Spleen That Is Regulated by NR4A1.Periostin in the pathogenesis of skin diseases.Aucubin Alleviates Bleomycin-Induced Pulmonary Fibrosis in a Mouse Model.The stress-induced transcription factor NR4A1 adjusts mitochondrial function and synapse number in prefrontal cortex.TGF-β signaling in cancer metastasis.Induction of IL-10 by Borrelia burgdorferi is regulated by the action of CD14-dependent p38-MAPK and cAMP-mediated chromatin remodeling.Molecular and cellular mechanisms of glucagon-like peptide-1 receptor agonist-mediated attenuation of cardiac fibrosis.
P2860
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P2860
Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Orphan nuclear receptor NR4A1 ...... ctor-β signaling and fibrosis.
@en
type
label
Orphan nuclear receptor NR4A1 ...... ctor-β signaling and fibrosis.
@en
prefLabel
Orphan nuclear receptor NR4A1 ...... ctor-β signaling and fibrosis.
@en
P2093
P2860
P50
P356
P1433
P1476
Orphan nuclear receptor NR4A1 ...... ctor-β signaling and fibrosis.
@en
P2093
Alfiya Distler
Barbara G Fürnrohr
Carina Scholtysek
Christian Beyer
Clara Dees
Dirk Mielenz
Jingang Huang
Judith Fliehr
Jörg H W Distler
Katrin Palumbo-Zerr
P2860
P2888
P304
P356
10.1038/NM.3777
P407
P577
2015-01-12T00:00:00Z