A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug-induced liver injury and postinjury inflammation in mice.
about
Drug-induced liver injury: Advances in mechanistic understanding that will inform risk management.Mechanisms of acetaminophen hepatotoxicity and their translation to the human pathophysiology.Key Events Participating in the Pathogenesis of Alcoholic Liver Disease.The transformation in biomarker detection and management of drug-induced liver injuryHMGB1 is a promising therapeutic target for acute liver failure.HMGB1 and Extracellular Histones Significantly Contribute to Systemic Inflammation and Multiple Organ Failure in Acute Liver FailureCyclic stretch induced IL-33 production through HMGB1/TLR-4 signaling pathway in murine respiratory epithelial cells.Real-time in vivo imaging reveals localised Nrf2 stress responses associated with direct and metabolism-dependent drug toxicity.Risk stratification after paracetamol overdose using mechanistic biomarkers: results from two prospective cohort studies.Hepatic mitochondrial DNA/Toll-like receptor 9/MicroRNA-223 forms a negative feedback loop to limit neutrophil overactivation and acetaminophen hepatotoxicity in mice.Ligation of free HMGB1 to TLR2 in the absence of ligand is negatively regulated by the C-terminal tail domain.Paracetamol metabolism, hepatotoxicity, biomarkers and therapeutic interventions: a perspectiveHigh-Mobility Group Box-1 and Liver Disease
P2860
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P2860
A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug-induced liver injury and postinjury inflammation in mice.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
A novel high mobility group bo ...... stinjury inflammation in mice.
@en
type
label
A novel high mobility group bo ...... stinjury inflammation in mice.
@en
prefLabel
A novel high mobility group bo ...... stinjury inflammation in mice.
@en
P2093
P2860
P50
P356
P1433
P1476
A novel high mobility group bo ...... stinjury inflammation in mice.
@en
P2093
Agnieszka Sowinska
Anna M Blom
B Kevin Park
Cecilia Aulin
Daniel J Antoine
Helena Erlandsson Harris
Joanna I Clarke
Johanna Steen
Jonathan D Lea
P2860
P304
P356
10.1002/HEP.28736
P407
P577
2016-07-30T00:00:00Z