about
Structure determination of group II introns.A Genetic Screen for Pre-mRNA Splicing Mutants of Arabidopsis thaliana Identifies Putative U1 snRNP Components RBM25 and PRP39a.Structure of the yeast spliceosomal postcatalytic P complex.Development of an in vitro pre-mRNA splicing assay using plant nuclear extract.Postcatalytic spliceosome structure reveals mechanism of 3'-splice site selection.The life of U6 small nuclear RNA, from cradle to grave.Structure of the human activated spliceosome in three conformational states.Insights from structures of cancer-relevant pre-mRNA splicing factors.The RES complex is required for efficient transformation of the precatalytic B spliceosome into an activated Bact complex.The cryo-EM structure of the SF3b spliceosome complex bound to a splicing modulator reveals a pre-mRNA substrate competitive mechanism of action.Intrinsically Disordered Protein Ntr2 Modulates the Spliceosomal RNA Helicase Brr2.Defining essential elements and genetic interactions of the yeast Lsm2-8 ring and demonstration that essentiality of Lsm2-8 is bypassed via overexpression of U6 snRNA or the U6 snRNP subunit Prp24.Prp8 positioning of U5 snRNA is linked to 5' splice site recognition.Structural dynamics of the N-terminal domain and the Switch loop of Prp8 during spliceosome assembly and activation.Characterisation of molecular motions in cryo-EM single-particle data by multi-body refinement in RELION.Approaches to altering particle distributions in cryo-electron microscopy sample preparationPrespliceosome structure provides insights into spliceosome assembly and regulation
P2860
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P2860
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年論文
@yue
2017年論文
@zh-hant
2017年論文
@zh-hk
2017年論文
@zh-mo
2017年論文
@zh-tw
2017年论文
@wuu
2017年论文
@zh
2017年论文
@zh-cn
name
Structure of a pre-catalytic spliceosome.
@en
type
label
Structure of a pre-catalytic spliceosome.
@en
prefLabel
Structure of a pre-catalytic spliceosome.
@en
P2860
P356
P1433
P1476
Structure of a pre-catalytic spliceosome.
@en
P2093
Kiyoshi Nagai
Pei-Chun Lin
P2860
P2888
P304
P356
10.1038/NATURE22799
P407
P577
2017-05-22T00:00:00Z
P6179
1085537692