Pharmacokinetic analysis of felodipine-grapefruit juice interaction based on an irreversible enzyme inhibition model - Wikidata - awgldk - TriplyDB

Pharmacokinetic analysis of felodipine-grapefruit juice interaction based on an irreversible enzyme inhibition model

Pharmacokinetic analysis of felodipine-grapefruit juice interaction based on an irreversible enzyme inhibition model

http://www.wikidata.org/entity/Q41609746

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Medicinal importance of grapefruit juice and its interaction with various drugs Physiologically based pharmacokinetic model of mechanism-based inhibition of CYP3A by clarithromycin Population pharmacokinetics of lopinavir in combination with ritonavir in HIV-1-infected patients Pharmacokinetic modelling of the interaction between St John's wort and ciclosporin A.Grapefruit-drug interactions: can interactions with drugs be avoided?Clinical relevance of the small intestine as an organ of drug elimination: drug-fruit juice interactions.Interactions of grapefruit juice and cardiovascular medications: A potential risk of toxicity.Cytochrome P450 time-dependent inhibition and induction: advances in assays, risk analysis and modelling.Effect of grapefruit juice on the pharmacokinetics of nilotinib in healthy participants.In-vivo kinetics of the interaction between midazolam and erythromycin in rats, taking account of metabolic intermediate complex formation.Powder-in-bottle formulation of SU011248. Enabling rapid progression into human clinical trials.Development of an Adult Physiologically Based Pharmacokinetic Model of Solithromycin in Plasma and Epithelial Lining Fluid.Pomegranate juice does not impair clearance of oral or intravenous midazolam, a probe for cytochrome P450-3A activity: comparison with grapefruit juice.

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P2860

Pharmacokinetic analysis of felodipine-grapefruit juice interaction based on an irreversible enzyme inhibition model

http://www.wikidata.org/entity/Q41609746

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2000 nî lūn-bûn

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J.1365-2125.2000.00140.X

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British Journal of Clinical Pharmacology

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Pharmacokinetic analysis of fe ...... rsible enzyme inhibition model

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A Ohnishi

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A Urae

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Y Sawada

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P2860

Inhibitory effect of grapefruit juice and its bitter principal, naringenin, on CYP1A2 dependent metabolism of caffeine in man.

Inactivation of cytochrome P450 3A4 by bergamottin, a component of grapefruit juice

Relationship between time of intake of grapefruit juice and its effect on pharmacokinetics and pharmacodynamics of felodipine in healthy subjects

Trough concentrations of cyclosporine in blood following administration with grapefruit juice.

Factors affecting the absolute bioavailability of nifedipine.

Effects of grapefruit juice ingestion--pharmacokinetics and haemodynamics of intravenously and orally administered felodipine in healthy men.

Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents. Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins.

Interaction of citrus juices with felodipine and nifedipine.

Grapefruit juice enhances the bioavailability of the HIV protease inhibitor saquinavir in man

Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression.

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