Dyrk1 inhibition improves Alzheimer's disease-like pathology.

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description

2017 nî lūn-bûn

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2017年の論文

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2017年論文

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2017年論文

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2017年論文

@zh-hk

2017年論文

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2017年論文

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2017年论文

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2017年论文

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2017年论文

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name

Dyrk1 inhibition improves Alzheimer's disease-like pathology.

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type

Item

label

Dyrk1 inhibition improves Alzheimer's disease-like pathology.

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prefLabel

Dyrk1 inhibition improves Alzheimer's disease-like pathology.

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P1476

Dyrk1 inhibition improves Alzheimer's disease-like pathology

@en

P2093

Antonella Caccamo

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Arthur Y Shaw

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Bessie Meechoovet

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Breland Smith

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Caterina Branca

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Christopher Hulme

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Darren M Shaw

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Ramona Belfiore

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Salvatore Oddo

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Travis Dunckley

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P2860

Alzheimer's Disease

The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bepsilon at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen synthase kinase 3-priming kinase

DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down Syndrome

New Features about Tau Function and Dysfunction

Case report of novel DYRK1A mutations in 2 individuals with syndromic intellectual disability and a review of the literature

Administration of a selective β2 adrenergic receptor antagonist exacerbates neuropathology and cognitive deficits in a mouse model of Alzheimer's disease

β-carboline compounds, including harmine, inhibit DYRK1A and tau phosphorylation at multiple Alzheimer's disease-related sites

A chemical with proven clinical safety rescues Down-syndrome-related phenotypes in through DYRK1A inhibition

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

Alzheimer's Disease in Down Syndrome.

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1146-1154

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scholarly article

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10.1111/ACEL.12648

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P433

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P478

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Christopher Foley

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2017-08-04T00:00:00Z

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28779511

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P921

Alzheimer's disease

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5595697

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