Adaptive Reprogramming of De Novo Pyrimidine Synthesis Is a Metabolic Vulnerability in Triple-Negative Breast Cancer.
about
ASCT2 regulates glutamine uptake and cell growth in endometrial carcinomamTORC1 Couples Nucleotide Synthesis to Nucleotide Demand Resulting in a Targetable Metabolic Vulnerability.Targeting Metabolism for Cancer Therapy.The anti-rheumatic drug, leflunomide, synergizes with MEK inhibition to suppress melanoma growth.Nuclear Acetyl-CoA Production by ACLY Promotes Homologous Recombination.A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.Alternative assembly of respiratory complex II connects energy stress to metabolic checkpoints.Identification of an immune gene expression signature associated with favorable clinical features in Treg-enriched patient tumor samples.Triple-negative breast cancer and the potential for targeted therapyMetabolic vulnerability of cisplatin-resistant cancersPharmacological inhibition of dihydroorotate dehydrogenase induces apoptosis and differentiation in acute myeloid leukemia cellsTargeting dihydroorotate dehydrogenase in acute myeloid leukemia
P2860
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P2860
Adaptive Reprogramming of De Novo Pyrimidine Synthesis Is a Metabolic Vulnerability in Triple-Negative Breast Cancer.
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年論文
@yue
2017年論文
@zh-hant
2017年論文
@zh-hk
2017年論文
@zh-mo
2017年論文
@zh-tw
2017年论文
@wuu
2017年论文
@zh
2017年论文
@zh-cn
name
Adaptive Reprogramming of De N ...... Triple-Negative Breast Cancer.
@en
type
label
Adaptive Reprogramming of De N ...... Triple-Negative Breast Cancer.
@en
prefLabel
Adaptive Reprogramming of De N ...... Triple-Negative Breast Cancer.
@en
P2093
P2860
P1433
P1476
Adaptive Reprogramming of De N ...... Triple-Negative Breast Cancer.
@en
P2093
Alex Toker
Jessica B Spinelli
John M Asara
P2860
P304
P356
10.1158/2159-8290.CD-16-0611
P577
2017-03-02T00:00:00Z