The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules.
about
CAST, a novel CD3epsilon-binding protein transducing activation signal for interleukin-2 production in T cellsThe transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chainInduced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell deathZAP-70 binding specificity to T cell receptor tyrosine-based activation motifs: the tandem SH2 domains of ZAP-70 bind distinct tyrosine-based activation motifs with varying affinityT cell receptor (TCR) interacting molecule (TRIM), a novel disulfide-linked dimer associated with the TCR-CD3-zeta complex, recruits intracellular signaling proteins to the plasma membraneAnalysis of the interaction of ZAP-70 and syk protein-tyrosine kinases with the T-cell antigen receptor by plasmon resonanceGene structure of mouse BIT/SHPS-1Dual role of the tyrosine activation motif of the Ig-alpha protein during signal transduction via the B cell antigen receptorBinding of ZAP-70 to phosphorylated T-cell receptor zeta and eta enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteinsT cell activationPhysical dissociation of the TCR-CD3 complex accompanies receptor ligationDifferent roles for the Fc epsilon RI gamma chain as a function of the receptor contextT cell receptor zeta/CD3-p59fyn(T)-associated p120/130 binds to the SH2 domain of p59fyn(T)Differential association of cytoplasmic signalling molecules SHP-1, SHP-2, SHIP and phospholipase C-gamma1 with PECAM-1/CD31Two distinct intracytoplasmic regions of the T-cell adhesion molecule CD28 participate in phosphatidylinositol 3-kinase associationSpecific interaction of topoisomerase II beta and the CD3 epsilon chain of the T cell receptor complexInteractions of p59fyn and ZAP-70 with T-cell receptor activation motifs: defining the nature of a signalling motifTargeted disruption of the CD3 eta locus causes high lethality in mice: modulation of Oct-1 transcription on the opposite strandCD45 and RPTPalpha display different protein tyrosine phosphatase activities in T lymphocytesCD22 associates with the human surface IgM-B-cell antigen receptor complexQuantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hubPhosphorylated T cell receptor zeta-chain and ZAP70 tandem SH2 domains form a 1:3 complex in vitroThe adaptor protein SAP directly associates with CD3ζ chain and regulates T cell receptor signaling.Evidence for a functional sidedness to the alphabetaTCR.The CD3 zeta subunit contains a phosphoinositide-binding motif that is required for the stable accumulation of TCR-CD3 complex at the immunological synapse.Conserved transmembrane tyrosine residues of the TCR beta chain are required for TCR expression and function in primary T cells and hybridomas.Engineering higher affinity T cell receptors using a T cell display system.High-level variability in the ORF-K1 membrane protein gene at the left end of the Kaposi's sarcoma-associated herpesvirus genome defines four major virus subtypes and multiple variants or clades in different human populationsRole of CD45 signaling pathway in galactoxylomannan-induced T cell damage.Human immunodeficiency virus type 2 produces a defect in CD3-gamma gene transcripts similar to that observed for human immunodeficiency virus type 1.ITAM-mediated signaling by the T-cell antigen receptorEngagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains.Role of associated gamma-chain in tyrosine kinase activation via murine Fc gamma RIIICD45 tyrosine phosphatase-activated p59fyn couples the T cell antigen receptor to pathways of diacylglycerol production, protein kinase C activation and calcium influxDevelopment and function of T cells in mice with a disrupted CD2 geneCell surface control of the multiubiquitination and deubiquitination of high-affinity immunoglobulin E receptorsNormal development and function of natural killer cells in CD3 epsilon delta 5/delta 5 mutant mice.The (YXXL/I)2 signalling motif found in the cytoplasmic segments of the bovine leukaemia virus envelope protein and Epstein-Barr virus latent membrane protein 2A can elicit early and late lymphocyte activation events.Direct evidence to support the immunosurveillance concept in a human regressive melanoma.Piecing together the family portrait of TCR-CD3 complexes.
P2860
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P2860
The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
The T cell receptor/CD3 comple ...... tonomous transduction modules.
@en
type
label
The T cell receptor/CD3 comple ...... tonomous transduction modules.
@en
prefLabel
The T cell receptor/CD3 comple ...... tonomous transduction modules.
@en
P2093
P1433
P1476
The T cell receptor/CD3 comple ...... utonomous transduction modules
@en
P2093
P356
10.1016/0092-8674(92)90208-T
P407
P577
1992-01-01T00:00:00Z