TDP-43 loss of function inhibits endosomal trafficking and alters trophic signaling in neurons.
about
Tdp-43 cryptic exons are highly variable between cell types.Sense-encoded poly-GR dipeptide repeat proteins correlate to neurodegeneration and uniquely co-localize with TDP-43 in dendrites of repeat-expanded C9orf72 amyotrophic lateral sclerosis.Endocytosis regulates TDP-43 toxicity and turnover.U6 snRNA expression prevents toxicity in TDP-43-knockdown cells.TDP-43 misexpression causes defects in dendritic growth.Towards a TDP-43-Based Biomarker for ALS and FTLD.An optimised version of the secretome protein enrichment with click sugars (SPECS) method leads to enhanced coverage of the secretome.New approaches for solving old problems in neuronal protein trafficking.TAR DNA Binding Protein-43 Loss of Function Induced by Phosphorylation at S409/410 Blocks Autophagic Flux and Participates in Secondary Brain Injury After Intracerebral Hemorrhage.Amyotrophic lateral sclerosisIncreased Microglial Activity, Impaired Adult Hippocampal Neurogenesis, and Depressive-like Behavior in Microglial VPS35-Depleted Mice
P2860
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P2860
TDP-43 loss of function inhibits endosomal trafficking and alters trophic signaling in neurons.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
TDP-43 loss of function inhibi ...... trophic signaling in neurons.
@en
type
label
TDP-43 loss of function inhibi ...... trophic signaling in neurons.
@en
prefLabel
TDP-43 loss of function inhibi ...... trophic signaling in neurons.
@en
P2093
P2860
P50
P356
P1433
P1476
TDP-43 loss of function inhibi ...... trophic signaling in neurons.
@en
P2093
Alessio Colombo
Alperen Serdaroglu
Benjamin M Schwenk
Clemens Küpper
Daniel Hornburg
Denise Orozco
Felix Meissner
Franziska Schreiber
Hannelore Hartmann
Markus Otto
P2860
P304
P356
10.15252/EMBJ.201694221
P407
P577
2016-09-12T00:00:00Z