A versatile mismatch recognition agent: specific cleavage of a plasmid DNA at a single base mispair.
about
The path for metal complexes to a DNA targetImidazole-imidazole pair as a minor groove recognition motif for T:G mismatched base pairsInsights into finding a mismatch through the structure of a mispaired DNA bound by a rhodium intercalatorA Bulky Rhodium Complex Bound to an Adenosine-Adenosine DNA Mismatch: General Architecture of the Metalloinsertion Binding ModeLuminescent properties of ruthenium(II) complexes with sterically expansive ligands bound to DNA defects.An unusual ligand coordination gives rise to a new family of rhodium metalloinsertors with improved selectivity and potency.A monofunctional platinum complex coordinated to a rhodium metalloinsertor selectively binds mismatched DNA in the minor groove.Targeting DNA Mismatches with Rhodium Metalloinsertors.Thymine dimer-induced structural changes to the DNA duplex examined with reactive probes (†).A rhodium(III) complex for high-affinity DNA base-pair mismatch recognitionDNA mismatch-specific targeting and hypersensitivity of mismatch-repair-deficient cells to bulky rhodium(III) intercalators.Hidden in plain sight: subtle effects of the 8-oxoguanine lesion on the structure, dynamics, and thermodynamics of a 15-base pair oligodeoxynucleotide duplex.Chemistry challenges in SNP typing.Luminescent platinum(II) complexes with functionalized N-heterocyclic carbene or diphosphine selectively probe mismatched and abasic DNA.Metallo-intercalators and metallo-insertorsCell-selective biological activity of rhodium metalloinsertors correlates with subcellular localizationBinding of Ru(bpy)2(eilatin)2+ to matched and mismatched DNA.Insertion of a bulky rhodium complex into a DNA cytosine-cytosine mismatch: an NMR solution study.DNA base mismatch detection with bulky rhodium intercalators: synthesis and applications.Single-nucleotide polymorphism discovery by targeted DNA photocleavage.Finding needles in a basestack: recognition of mismatched base pairs in DNA by small molecules.Recognition of T*G mismatched base pairs in DNA by stacked imidazole-containing polyamides: surface plasmon resonance and circular dichroism studies.DNA strand cleavage near a CC mismatch directed by a metalloinsertorLuminescence of [Ru(bpy)2(dppz)]2+ bound to RNA mismatches.Sensitivity of Ru(bpy)2dppz2+ luminescence to DNA defects.DNA mismatch binding and antiproliferative activity of rhodium metalloinsertors.An amplification and ligation-based method to scan for unknown mutations in DNA.Detection of guanine-adenine mismatches by surface plasmon resonance sensor carrying naphthyridine-azaquinolone hybrid on the surface.Biological effects of simple changes in functionality on rhodium metalloinsertors.Probing nucleic acid structure with shape-selective rhodium and ruthenium complexes.Targeting abasic sites and single base bulges in DNA with metalloinsertors.Ruthenium(II) [3 + 2 + 1] mixed ligand complexes: substituent effect on photolability, photooxidation of bases, photocytotoxicity and photonuclease activity.Targeted Chemotherapy with Metal Complexes.Macrocyclic DNA-mismatch-binding ligands: structural determinants of selectivity.Two-level system with a thermally fluctuating transfer matrix element: application to the problem of DNA charge transfer.A Rhodium-Cyanine Fluorescent Probe: Detection and Signaling of Mismatches in DNA.Hereditary stability and variation in evolution and development.A Family of Rhodium Complexes with Selective Toxicity toward Mismatch Repair-Deficient Cancers.Synthesis, DNA binding, and cleavage studies of Co(III) complexes with fused aromatic NO/NN-containing ligands.DNA Binding by a New Metallointercalator that Contains a Proflavine Group Bearing a Hanging Chelating Unit
P2860
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P2860
A versatile mismatch recognition agent: specific cleavage of a plasmid DNA at a single base mispair.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
A versatile mismatch recogniti ...... DNA at a single base mispair.
@en
type
label
A versatile mismatch recogniti ...... DNA at a single base mispair.
@en
prefLabel
A versatile mismatch recogniti ...... DNA at a single base mispair.
@en
P2093
P356
P1433
P1476
A versatile mismatch recogniti ...... DNA at a single base mispair.
@en
P2093
Alekseyev VY
Jackson BA
P304
P356
10.1021/BI990255T
P407
P577
1999-04-01T00:00:00Z