Divalent cation regulation of the function of the leukocyte integrin LFA-1
about
Specific activation of leukocyte beta2 integrins lymphocyte function-associated antigen-1 and Mac-1 by chemokines mediated by distinct pathways via the alpha subunit cytoplasmic domainsAnthrax toxin receptor 1/tumor endothelium marker 8 mediates cell spreading by coupling extracellular ligands to the actin cytoskeletonCrystal structure of the I-domain from the CD11a/CD18 (LFA-1, alpha L beta 2) integrinCytohesin-1 regulates beta-2 integrin-mediated adhesion through both ARF-GEF function and interaction with LFA-1Leukocyte integrins: role in leukocyte recruitment and as therapeutic targets in inflammatory diseaseAdhesive F-actin waves: a novel integrin-mediated adhesion complex coupled to ventral actin polymerizationSelection and structure of ion-selective ligands for platelet integrin alpha IIb(beta) 3Stable Coordination of the Inhibitory Ca2+ Ion at the Metal Ion-Dependent Adhesion Site in Integrin CD11b/CD18 by an Antibody-Derived Ligand Aspartate: Implications for Integrin Regulation and Structure-Based Drug DesignJAM2 interacts with alpha4beta1. Facilitation by JAM3Association of the membrane proximal regions of the alpha and beta subunit cytoplasmic domains constrains an integrin in the inactive stateDistinct roles for the alpha and beta subunits in the functions of integrin alphaMbeta2A biochemical characterization of the binding of osteopontin to integrins alpha v beta 1 and alpha v beta 5The immune dysregulatory compound mercuric chloride induces integrin-mediated T-lymphocyte adhesionRolling on E- or P-selectin induces the extended but not high-affinity conformation of LFA-1 in neutrophilsAn essential role for calcium flux in phagocytes for apoptotic cell engulfment and the anti-inflammatory responseSpecific and covalent labeling of a membrane protein with organic fluorochromes and quantum dotsIntermediate-affinity LFA-1 binds alpha-actinin-1 to control migration at the leading edge of the T cell.Polarized localization of epithelial CXCL11 in chronic obstructive pulmonary disease and mechanisms of T cell egressionIntegrin alpha IIb beta 3 in a membrane environment remains the same height after Mn2+ activation when observed by cryoelectron tomography.Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation.Macrophages require Skap2 and Sirpα for integrin-stimulated cytoskeletal rearrangement.Small molecule agonists of integrin CD11b/CD18 do not induce global conformational changes and are significantly better than activating antibodies in reducing vascular injury.Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor.Lateral Mobility and Nanoscale Spatial Arrangement of Chemokine-activated α4β1 Integrins on T CellsThe N-terminal region and the mid-region complex of the integrin beta 2 subunit.Characteristics of cation binding to the I domains of LFA-1 and MAC-1. The LFA-1 I domain contains a Ca2+-binding site.Identification and characterization of a human monoclonal antagonistic antibody AL-57 that preferentially binds the high-affinity form of lymphocyte function-associated antigen-1.Combinatorial libraries against libraries for selecting neoepitope activation-specific antibodies.Modulation of human immunodeficiency virus type 1-induced syncytium formation by the conformational state of LFA-1 determined by a new luciferase-based syncytium quantitative assayLong-lived, high-strength states of ICAM-1 bonds to beta2 integrin, II: lifetimes of LFA-1 bonds under force in leukocyte signalingEnterococcus faecalis bearing aggregation substance is resistant to killing by human neutrophils despite phagocytosis and neutrophil activationEpstein-Barr virus infection of polarized epithelial cells via the basolateral surface by memory B cell-mediated transfer infection.FRET based quantification and screening technology platform for the interactions of leukocyte function-associated antigen-1 (LFA-1) with intercellular adhesion molecule-1 (ICAM-1).The small GTPase Rap1 is required for Mn(2+)- and antibody-induced LFA-1- and VLA-4-mediated cell adhesion.Demystified...adhesion molecule deficiencies.Micromechanical tests of adhesion dynamics between neutrophils and immobilized ICAM-1Neutrophil adhesive contact dependence on impingement force.Shifts in the concentrations of magnesium and calcium in early porcine and rat wound fluids activate the cell migratory responseAnalysis of the binding site on intercellular adhesion molecule 3 for the leukocyte integrin lymphocyte function-associated antigen 1.Leukocyte adhesion--structure and function of human leukocyte beta2-integrins and their cellular ligands.
P2860
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P2860
Divalent cation regulation of the function of the leukocyte integrin LFA-1
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Divalent cation regulation of the function of the leukocyte integrin LFA-1
@en
type
label
Divalent cation regulation of the function of the leukocyte integrin LFA-1
@en
prefLabel
Divalent cation regulation of the function of the leukocyte integrin LFA-1
@en
P2093
P2860
P356
P1476
Divalent cation regulation of the function of the leukocyte integrin LFA-1
@en
P2093
P2860
P304
P356
10.1083/JCB.116.1.219
P407
P577
1992-01-01T00:00:00Z