Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome.
about
Transcription repression by Xenopus ET and its human ortholog TBX3, a gene involved in ulnar-mammary syndromeZHX proteins regulate podocyte gene expression during the development of nephrotic syndromeInhibition of cellular proliferation by the Wilms tumor suppressor WT1 requires association with the inducible chaperone Hsp70PAX8-mediated activation of the wt1 tumor suppressor geneWT1 suppresses synthesis of the epidermal growth factor receptor and induces apoptosisDuplicated KOX zinc finger gene clusters flank the centromere of human chromosome 10: evidence for a pericentric inversion during primate evolutionHuman platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1Zinc finger point mutations within the WT1 gene in Wilms tumor patientsMutagenic effects of a single and an exact number of alpha particles in mammalian cellsPelizaeus-Merzbacher disease: detection of mutations Thr181----Pro and Leu223----Pro in the proteolipid protein gene, and prenatal diagnosisInduction of a bystander mutagenic effect of alpha particles in mammalian cellsOpportunities and Challenges of Genotyping Patients With Nephrotic Syndrome in the Genomic EraCell biology and pathology of podocytesGenes and podocytes - new insights into mechanisms of podocytopathyDenys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modificationsMonoallelic expression of the human H19 geneCretinism with combined hormone deficiency caused by a mutation in the PIT1 geneA germline mutation in the androgen receptor gene in two brothers with breast cancer and Reifenstein syndromeThe Denys-Drash syndromeAPOBEC3A is implicated in a novel class of G-to-A mRNA editing in WT1 transcriptsWT1-dependent sulfatase expression maintains the normal glomerular filtration barrierTranscriptional regulation by the Wilms tumor protein, Wt1, suggests a role of the metalloproteinase Adamts16 in murine genitourinary developmentPolycystin 1 is required for the structural integrity of blood vesselsThe ovo gene required for cuticle formation and oogenesis in flies is involved in hair formation and spermatogenesis in miceMendelian cytogenetics. Chromosome rearrangements associated with mendelian disordersDisentangling genetic vs. environmental causes of sex determination in the common frog, Rana temporariaHuman sex determination.WT1 mutation as a cause of 46 XY DSD and Wilm's tumour: a case report and literature review.Long arm deletion of chromosome 10 in a boy with monorchidism.Deletion 9p and sex reversal.Mutational screening of the Wilms's tumour gene, WT1, in males with genital abnormalities.A dominant mutation in the Wilms tumor gene WT1 cooperates with the viral oncogene E1A in transformation of primary kidney cells.Truncated WT1 mutants alter the subnuclear localization of the wild-type protein.An autosomal or X linked mutation results in true hermaphrodites and 46,XX males in the same familyDo intronic mutations affecting splicing of WT1 exon 9 cause Frasier syndrome?Rapid detection of monogenic causes of childhood-onset steroid-resistant nephrotic syndrome.Antagonism of WT1 activity by protein self-association.A novel WT1 gene mutation in a three-generation family with progressive isolated focal segmental glomerulosclerosis.Recurrent somatic mutation in DROSHA induces microRNA profile changes in Wilms tumourCharacterization of the Zn(II) binding properties of the human Wilms' tumor suppressor protein C-terminal zinc finger peptide
P2860
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P2860
Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Germline mutations in the Wilm ...... pment in Denys-Drash syndrome.
@en
type
label
Germline mutations in the Wilm ...... pment in Denys-Drash syndrome.
@en
prefLabel
Germline mutations in the Wilm ...... pment in Denys-Drash syndrome.
@en
P2093
P1433
P1476
Germline mutations in the Wilm ...... pment in Denys-Drash syndrome.
@en
P2093
Bruening W
Houghton DC
Kashtan CE
Manivel JC
Pelletier J
Striegel JE
P304
P356
10.1016/0092-8674(91)90194-4
P407
P577
1991-10-01T00:00:00Z