Recent explosive human population growth has resulted in an excess of rare genetic variants.
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Genomic identification of founding haplotypes reveals the history of the selfing species Capsella rubellaRecombination affects accumulation of damaging and disease-associated mutations in human populationsAn integrated map of genetic variation from 1,092 human genomesAnalyses of pig genomes provide insight into porcine demography and evolutionThe great human expansionGenetic Misdiagnoses and the Potential for Health DisparitiesGenetic disruption of voltage-gated calcium channels in psychiatric and neurological disordersCurrent and Prospective Methods for Plant Disease DetectionChallenges in medical applications of whole exome/genome sequencing discoveriesExome sequencing and complex disease: practical aspects of rare variant association studiesExplosive genetic evidence for explosive human population growthUnderstanding rare and common diseases in the context of human evolutionThe genetic heterogeneity of colorectal cancer predisposition - guidelines for gene discoveryA recent bottleneck of Y chromosome diversity coincides with a global change in cultureRegional Differences in the Accumulation of SNPs on the Male-Specific Portion of the Human Y Chromosome Replicate Autosomal Patterns: Implications for Genetic Dating267 Spanish Exomes Reveal Population-Specific Differences in Disease-Related Genetic VariationCharacterization of population-based variation and putative functional elements for the multiple-cancer susceptibility loci at 5p15.33Aberrant gene expression in humansInferring Past Effective Population Size from Distributions of Coalescent TimesY-chromosome phylogeographic analysis of the Greek-Cypriot population reveals elements consistent with Neolithic and Bronze Age settlementsThe aggregate site frequency spectrum for comparative population genomic inferenceHost genetic variation impacts microbiome composition across human body sitesMultidisciplinary approach to genomics research in Africa: the AfriCRAN modelCarriers of Mitochondrial DNA Macrohaplogroup N Lineages Reached Australia around 50,000 Years Ago following a Northern Asian RouteLow-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibilityOn the need for mechanistic models in computational genomics and metagenomicsWhy to account for finite sites in population genetic studies and how to do this with Jaatha 2.0Origin and demographic history of the endemic Taiwan spruce (Picea morrisonicola)Properties and rates of germline mutations in humansRare variation facilitates inferences of fine-scale population structure in humans.Exploration of pathomechanisms triggered by a single-nucleotide polymorphism in titin's I-band: the cardiomyopathy-linked mutation T2580I.Exome sequencing of germline DNA from non-BRCA1/2 familial breast cancer cases selected on the basis of aCGH tumor profiling.Global migration and the changing distribution of sickle haemoglobin: a quantitative study of temporal trends between 1960 and 2000.Improving the accuracy and efficiency of identity-by-descent detection in population dataThe low frequency of recessive disease: insights from ENU mutagenesis, severity of disease phenotype, GWAS associations, and demography: an analytical review.An overview of the utility of population simulation software in molecular ecology.A generalized least-squares framework for rare-variant analysis in family dataEfficient inference of population size histories and locus-specific mutation rates from large-sample genomic variation data.Genotype-Frequency Estimation from High-Throughput Sequencing Data.Efficient genotype compression and analysis of large genetic-variation data sets.
P2860
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P2860
Recent explosive human population growth has resulted in an excess of rare genetic variants.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Recent explosive human populat ...... cess of rare genetic variants.
@en
type
label
Recent explosive human populat ...... cess of rare genetic variants.
@en
prefLabel
Recent explosive human populat ...... cess of rare genetic variants.
@en
P2860
P356
P1433
P1476
Recent explosive human populat ...... cess of rare genetic variants.
@en
P2093
Alon Keinan
Andrew G Clark
P2860
P304
P356
10.1126/SCIENCE.1217283
P407
P577
2012-05-01T00:00:00Z