Introduction of d-Glutamate at a Critical Residue of Aβ42 Stabilizes a Prefibrillary Aggregate with Enhanced Toxicity.
about
Identification of key regions and residues controlling Aβ folding and assembly.Using chirality to probe the conformational dynamics and assembly of intrinsically disordered amyloid proteins.Using chiral peptide substitutions to probe the structure function relationship of a key residue of Aβ42.Pyroglutamate and Isoaspartate modified Amyloid-Beta in ageing and Alzheimer's disease.Suppression of Oligomer Formation and Formation of Non-Toxic Fibrils upon Addition of Mirror-Image Aβ42 to the Natural l-Enantiomer.
P2860
Introduction of d-Glutamate at a Critical Residue of Aβ42 Stabilizes a Prefibrillary Aggregate with Enhanced Toxicity.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Introduction of d-Glutamate at ...... regate with Enhanced Toxicity.
@en
type
label
Introduction of d-Glutamate at ...... regate with Enhanced Toxicity.
@en
prefLabel
Introduction of d-Glutamate at ...... regate with Enhanced Toxicity.
@en
P2093
P2860
P356
P1476
Introduction of d-Glutamate at ...... gregate with Enhanced Toxicity
@en
P2093
Alejandro R Foley
Christopher J A Warner
Subrata Dutta
P2860
P304
11967-11970
P356
10.1002/CHEM.201601763
P407
P577
2016-06-30T00:00:00Z