Dissociation of beta 2-microglobulin leads to the accumulation of a substantial pool of inactive class I MHC heavy chains on the cell surface.
about
Macrophages present exogenous antigens by class I major histocompatibility complex molecules via a secretory pathway as a consequence of interferon-gamma activationExpression of the rat MHC class I gene in the human B lymphoblastoid cell line Hmy 2 CIRAn in vitro study of the dynamic features of the major histocompatibility complex class I complex relevant to its role as a versatile peptide-receptive moleculeAlternative pathways for processing exogenous and endogenous antigens that can generate peptides for MHC class I-restricted presentation.Skin graft rejection by beta 2-microglobulin-deficient mice.Efficient dissociation of the p88 chaperone from major histocompatibility complex class I molecules requires both beta 2-microglobulin and peptide.Cross-presentation: underlying mechanisms and role in immune surveillance.Direct delivery of exogenous MHC class I molecule-binding oligopeptides to the endoplasmic reticulum of viable cellsTumorigenicity conferred to lymphoma mutant by major histocompatibility complex-encoded transporter gene.Comparison of cell lines deficient in antigen presentation reveals a functional role for TAP-1 alone in antigen processing.Peptide influences the folding and intracellular transport of free major histocompatibility complex class I heavy chains.Intermediates in the assembly and degradation of class I major histocompatibility complex (MHC) molecules probed with free heavy chain-specific monoclonal antibodies.Cytokine Pattern of T Lymphocytes in Acute Schistosomiasis mansoni Patients following Treated Praziquantel Therapy.Dynamic equilibrium between vesicular stomatitis virus glycoprotein monomers and trimers in the Golgi and at the cell surface.Infection by polyomavirus of murine cells deficient in class I major histocompatibility complex expression.HLA-C is the inhibitory ligand that determines dominant resistance to lysis by NK1- and NK2-specific natural killer cellsGenome-wide association study identified the human leukocyte antigen region as a novel locus for plasma beta-2 microglobulin.Tumor necrosis factor α-induced hypoxia-inducible factor 1α-β-catenin axis regulates major histocompatibility complex class I gene activation through chromatin remodeling.Analysis of the association of peptides of optimal length to class I molecules on the surface of cellsMajor histocompatibility complex class I-specific and -restricted killing of beta 2-microglobulin-deficient cells by CD8+ cytotoxic T lymphocytes.Heat shock proteins can regulate expression of the Tla region-encoded class Ib molecule Qa-1.The use of signal peptide domains as vaccine candidatesImpaired intracellular transport and cell surface expression of nonpolymorphic HLA-E: evidence for inefficient peptide binding.A dominant negative mutant beta 2-microglobulin blocks the extracellular folding of a major histocompatibility complex class I heavy chain.Characterization of MHC Class I and β-2-Microglobulin Expression in Pediatric Solid Malignancies to Guide Selection of Immune-Based Therapeutic Trials.Delivery of protein antigen to the major histocompatibility complex class I-restricted antigen presentation pathway.Expression of immune genes in skin of channel catfish immunized with live theronts of Ichthyophthirius multifiliis.Beta2-micro-free HLA class I heavy chain levels in sera of healthy individuals. Lack of association with beta2-micro-associated HLA class I heavy chain levels and HLA phenotype.Expression of beta 2-microglobulin by human benign and malignant mesenchymal and neurogenic tumours.The interaction between beta 2-microglobulin (beta 2m) and purified class-I major histocompatibility (MHC) antigen.Regulation of MHC class I membrane expression by beta 2-microglobulin.The lymph as a pool of self-antigens.Folding and assembly of major histocompatibility complex class I heterodimers in the endoplasmic reticulum of intact cells precedes the binding of peptide.The CD8+ T cell repertoire in beta 2-microglobulin-deficient mice is biased towards reactivity against self-major histocompatibility class I.Major histocompatibility complex class I molecules modulate embryonic neuritogenesis and neuronal polarization.
P2860
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P2860
Dissociation of beta 2-microglobulin leads to the accumulation of a substantial pool of inactive class I MHC heavy chains on the cell surface.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Dissociation of beta 2-microgl ...... vy chains on the cell surface.
@en
type
label
Dissociation of beta 2-microgl ...... vy chains on the cell surface.
@en
prefLabel
Dissociation of beta 2-microgl ...... vy chains on the cell surface.
@en
P2093
P1433
P1476
Dissociation of beta 2-microgl ...... vy chains on the cell surface.
@en
P2093
P304
P356
10.1016/0092-8674(91)90093-E
P407
P577
1991-05-01T00:00:00Z