Genetic Alterations of the Thrombopoietin/MPL/JAK2 Axis Impacting Megakaryopoiesis.

about

JAK inhibitors for the treatment of myeloproliferative neoplasms and other disorders.

P2860

Q48109284-9F2383B7-E0FD-4C78-B76B-BBFDEFD958F8

P2860

Genetic Alterations of the Thrombopoietin/MPL/JAK2 Axis Impacting Megakaryopoiesis.

Item

http://www.wikidata.org/entity/Q41684028

description

2017 nî lūn-bûn

@nan

2017年の論文

@ja

2017年論文

@yue

2017年論文

@zh-hant

2017年論文

@zh-hk

2017年論文

@zh-mo

2017年論文

@zh-tw

2017年论文

@wuu

2017年论文

@zh

2017年论文

@zh-cn

name

Genetic Alterations of the Thrombopoietin/MPL/JAK2 Axis Impacting Megakaryopoiesis.

@en

type

Item

label

Genetic Alterations of the Thrombopoietin/MPL/JAK2 Axis Impacting Megakaryopoiesis.

@en

prefLabel

Genetic Alterations of the Thrombopoietin/MPL/JAK2 Axis Impacting Megakaryopoiesis.

@en

P1476

Genetic Alterations of the Thrombopoietin/MPL/JAK2 Axis Impacting Megakaryopoiesis.

@en

P2093

Caroline Marty

http://www.w3.org/2001/XMLSchema#string

Christine Bellanné-Chantelot

http://www.w3.org/2001/XMLSchema#string

Matthieu Mosca

http://www.w3.org/2001/XMLSchema#string

Stefania Mazzi

http://www.w3.org/2001/XMLSchema#string

P2860

Inhibition of Stat1-mediated gene activation by PIAS1

The thrombopoietin receptor P106L mutation functionally separates receptor signaling activity from thrombopoietin homeostasis

Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2

Crystal structures of the JAK2 pseudokinase domain and the pathogenic mutant V617F

Thrombopoietin signal transduction requires functional JAK2, not TYK2

Mutations in the thrombopoietin receptor, Mpl, in children with congenital amegakaryocytic thrombocytopenia

A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis

A gain-of-function mutation of JAK2 in myeloproliferative disorders

Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders

P304

234

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.3389/FENDO.2017.00234

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

William Vainchenker

Isabelle Plo

P577

2017-09-12T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

28955303

http://www.w3.org/2001/XMLSchema#string

P932

5600916

http://www.w3.org/2001/XMLSchema#string

Genetic Alterations of the Thrombopoietin/MPL/JAK2 Axis Impacting Megakaryopoiesis.

about

P2860

P2860

Genetic Alterations of the Thrombopoietin/MPL/JAK2 Axis Impacting Megakaryopoiesis.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P478

P50

P577

P698

P932