Enantioselectivity in the cytochrome P450-dependent conversion of tegafur to 5-fluorouracil in human liver microsomes.

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Species variation in the enantioselective metabolism of tegafur to 5-fluorouracil among rats, dogs and monkeys.

P2860

Q46852874-CE086062-4ED6-424C-AD52-05276DFC3C53

P2860

Enantioselectivity in the cytochrome P450-dependent conversion of tegafur to 5-fluorouracil in human liver microsomes.

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http://www.wikidata.org/entity/Q41692485

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2013 nî lūn-bûn

@nan

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

2013年论文

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2013年论文

@zh-cn

name

Enantioselectivity in the cyto ...... cil in human liver microsomes.

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type

Item

label

Enantioselectivity in the cyto ...... cil in human liver microsomes.

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Enantioselectivity in the cyto ...... cil in human liver microsomes.

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P1476

Enantioselectivity in the cyto ...... cil in human liver microsomes.

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P2093

Hideyuki Yamada

http://www.w3.org/2001/XMLSchema#string

Ikuo Yamamiya

http://www.w3.org/2001/XMLSchema#string

Ken-Ichiro Yoshida

http://www.w3.org/2001/XMLSchema#string

Kunihiro Yoshisue

http://www.w3.org/2001/XMLSchema#string

Yuji Ishii

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P2860

Involvement of microsomal cytochrome P450 and cytosolic thymidine phosphorylase in 5-fluorouracil formation from tegafur in human liver

Synthesis and biological activities of ftorafur metabolites. 3'- and 4'-hydroxyftorafur

In vitro inhibition of the cytochrome P450 (CYP450) system by the antiplatelet drug ticlopidine: potent effect on CYP2C19 and CYP2D6

Metabolic activation of R,S-1-(tetrahydro-2-furanyl)-5-fluorouracil (ftorafur) to 5-fluorouracil by soluble enzymes.

Comparison of (S)-mephenytoin and proguanil oxidation in vitro: contribution of several CYP isoforms.

Specificity of substrate and inhibitor probes for cytochrome P450s: evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes.

Formation pathways of gamma-butyrolactone from the furan ring of tegafur during its conversion to 5-fluorouracil.

Evaluation of methoxsalen, tranylcypromine, and tryptamine as specific and selective CYP2A6 inhibitors in vitro.

Stereoselective metabolism and pharmacokinetics of tegafur.

In vitro inhibitory effect of 1-aminobenzotriazole on drug oxidations catalyzed by human cytochrome P450 enzymes: a comparison with SKF-525A and ketoconazole.

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e00009

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scholarly article

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10.1002/PRP2.9

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P478

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2013-10-23T00:00:00Z

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264256763

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25505563

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enantioselectivity

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4184574

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Enantioselectivity in the cytochrome P450-dependent conversion of tegafur to 5-fluorouracil in human liver microsomes.

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P2860

P2860

Enantioselectivity in the cytochrome P450-dependent conversion of tegafur to 5-fluorouracil in human liver microsomes.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P5875

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P5875

P698

P921

P932