about
Integrative analysis of cyclin protein levels identifies cyclin b1 as a classifier and predictor of outcomes in breast cancerTP53 mutation is related to poor prognosis after radiotherapy, but not surgery, in squamous cell carcinoma of the head and neck.Mannan-binding lectin (MBL) and MBL-associated serine protease 2 (MASP-2) genotypes in colorectal cancerIndividual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumorsConducting radiogenomic research--do not forget careful consideration of the clinical data.Optimal reference genes for normalization of qRT-PCR data from archival formalin-fixed, paraffin-embedded breast tumors controlling for tumor cell content and decay of mRNA.Radiogenomics: radiobiology enters the era of big data and team science.Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients.Interaction between potential doubling time and TP53 mutation: predicting radiotherapy outcome in squamous cell carcinoma of the head and neck.Reproductive death of cancer cells induced by femtosecond laser pulses.In silico ascription of gene expression differences to tumor and stromal cells in a model to study impact on breast cancer outcome.In vivo identification and specificity assessment of mRNA markers of hypoxia in human and mouse tumorsEstablishment of a Radiogenomics Consortium.Does variability in normal tissue reactions after radiotherapy have a genetic basis--where and how to look for it?Importance of overall treatment time for the response to radiotherapy in patients with squamous cell carcinoma of the head and neck.Individual patient data meta-analysis shows no association between the SNP rs1800469 in TGFB and late radiotherapy toxicity.Characterization of an altered DNA catalysis of a camptothecin-resistant eukaryotic topoisomerase I.A Technical Assessment of the Utility of Reverse Phase Protein Arrays for the Study of the Functional Proteome in Non-microdissected Human Breast Cancers.Identifying microRNAs regulating B7-H3 in breast cancer: the clinical impact of microRNA-29c.Functional proteomics can define prognosis and predict pathologic complete response in patients with breast cancer.Simultaneous Hypoxia and Low Extracellular pH Suppress Overall Metabolic Rate and Protein Synthesis In VitroClinical Impact of a Novel MicroRNA Chemo-Sensitivity Predictor in Gastrooesophageal Cancer.Hypoxia in human soft tissue sarcomas: adverse impact on survival and no association with p53 mutations.Retinoblastoma protein expression is an independent predictor of both radiation response and survival in muscle-invasive bladder cancer.Carbonic anhydrase IX and response to postmastectomy radiotherapy in high-risk breast cancer: a subgroup analysis of the DBCG82 b and c trials.Antiproton radiotherapy.Genetic markers for prediction of normal tissue toxicity after radiotherapy.Genetic variants and normal tissue toxicity after radiotherapy: a systematic review.Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome.Hypoxia gene expression signatures as prognostic and predictive markers in head and neck radiotherapy.Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium.Mode of action of topoisomerase II-targeting agents at a specific DNA sequence. Uncoupling the DNA binding, cleavage and religation events.Activation of peroxisome proliferator-activated receptor gamma bypasses the function of the retinoblastoma protein in adipocyte differentiation.An evaluation of multiplex bead-based analysis of cytokines and soluble proteins in archived lithium heparin plasma, EDTA plasma and serum samples.Identification of accurate reference genes for RT-qPCR analysis of formalin-fixed paraffin-embedded tissue from primary non-small cell lung cancers and brain and lymph node metastases.Risk of radiation-induced subcutaneous fibrosis in relation to single nucleotide polymorphisms in TGFB1, SOD2, XRCC1, XRCC3, APEX and ATM--a study based on DNA from formalin fixed paraffin embedded tissue samples.Optimisation and validation of methods to assess single nucleotide polymorphisms (SNPs) in archival histological material.Validation of genetic predictors of late radiation-induced morbidity in prostate cancer patients.Hypoxia-regulated MicroRNAs in Gastroesophageal Cancer.A Gene Signature for Selecting Benefit from Hypoxia Modification of Radiotherapy for High-Risk Bladder Cancer Patients.
P50
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P50
description
hulumtues
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onderzoeker
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researcher
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հետազոտող
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name
Jan Alsner
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Jan Alsner
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Jan Alsner
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Jan Alsner
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Jan Alsner
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Jan Alsner
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Jan Alsner
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Jan Alsner
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Jan Alsner
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Jan Alsner
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Jan Alsner
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Jan Alsner
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P106
P1153
6603950959
P21
P31
P3835
jan-alsner
P496
0000-0002-5395-3193