Bastadin 10 stabilizes the open conformation of the ryanodine-sensitive Ca(2+) channel in an FKBP12-dependent manner.
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Insights into Chemistry of Biological Materials: Newly Discovered Silica-Aragonite-Chitin Biocomposites in DemospongesPara- and ortho-substitutions are key determinants of polybrominated diphenyl ether activity toward ryanodine receptors and neurotoxicityMinding the calcium store: Ryanodine receptor activation as a convergent mechanism of PCB toxicityThe marine bromotyrosine derivativesUnraveling the bastarane and isobastarane oximo amide configurations and associated macrocycle conformations: implications of their influence on bioactivitiesAltered elementary calcium release events and enhanced calcium release by thymol in rat skeletal muscleGreen tea catechins are potent sensitizers of ryanodine receptor type 1 (RyR1).Ablation of skeletal muscle triadin impairs FKBP12/RyR1 channel interactions essential for maintaining resting cytoplasmic Ca2+Ryanodine receptor point mutant E4032A reveals an allosteric interaction with ryanodine.Involvement of multiple intracellular release channels in calcium sparks of skeletal muscle.Role of Ryanodine and NMDA Receptors in Tetrabromobisphenol A-Induced Calcium Imbalance and Cytotoxicity in Primary Cultures of Rat Cerebellar Granule Cells.Simplified cyclic analogues of bastadin-5. Structure-activity relationships for modulation of the RyR1/FKBP12 Ca2+ channel complex.Cyclic versus hemi-bastadins. pleiotropic anti-cancer effects: from apoptosis to anti-angiogenic and anti-migratory effects.Ryanodine receptor type 1 (RyR1) possessing malignant hyperthermia mutation R615C exhibits heightened sensitivity to dysregulation by non-coplanar 2,2',3,5',6-pentachlorobiphenyl (PCB 95).Calcineurin regulates ryanodine receptor/Ca(2+)-release channels in rat heart.Maurocalcine and peptide A stabilize distinct subconductance states of ryanodine receptor type 1, revealing a proportional gating mechanism.Protein kinase A phosphorylation of the cardiac calcium release channel (ryanodine receptor) in normal and failing hearts. Role of phosphatases and response to isoproterenol.Differential effects of maurocalcine on Ca2+ release events and depolarization-induced Ca2+ release in rat skeletal muscle.An Extended Structure-Activity Relationship of Nondioxin-Like PCBs Evaluates and Supports Modeling Predictions and Identifies Picomolar Potency of PCB 202 Towards Ryanodine Receptors.
P2860
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P2860
Bastadin 10 stabilizes the open conformation of the ryanodine-sensitive Ca(2+) channel in an FKBP12-dependent manner.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Bastadin 10 stabilizes the ope ...... in an FKBP12-dependent manner.
@en
type
label
Bastadin 10 stabilizes the ope ...... in an FKBP12-dependent manner.
@en
prefLabel
Bastadin 10 stabilizes the ope ...... in an FKBP12-dependent manner.
@en
P2093
P2860
P356
P1476
Bastadin 10 stabilizes the ope ...... in an FKBP12-dependent manner.
@en
P2093
P2860
P304
32603-32612
P356
10.1074/JBC.274.46.32603
P407
P577
1999-11-01T00:00:00Z