The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans
about
Rule-based cell systems model of aging using feedback loop motifs mediated by stress responsesAMPK phosphorylation of raptor mediates a metabolic checkpointLessons from C. elegans: signaling pathways for longevityAMP-activated protein kinase, stress responses and cardiovascular diseasesmTOR is a key modulator of ageing and age-related diseaseReplicative and chronological aging in Saccharomyces cerevisiae.Extreme-longevity mutations orchestrate silencing of multiple signaling pathwaysAdenylate kinase and AMP signaling networks: metabolic monitoring, signal communication and body energy sensingNew genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen.Reprogramming of energy metabolism as a driver of agingLong live FOXO: unraveling the role of FOXO proteins in aging and longevityPerspective of Small-Molecule AdipoR Agonist for Type 2 Diabetes and Short Life in ObesityBiochemical Genetic Pathways that Modulate Aging in Multiple SpeciesAMP-activated protein kinase: an energy sensor that regulates all aspects of cell functionAMPK: a target for drugs and natural products with effects on both diabetes and cancerFLCN and AMPK Confer Resistance to Hyperosmotic Stress via Remodeling of Glycogen StoresThe Causative Gene in Chanarian Dorfman Syndrome Regulates Lipid Droplet Homeostasis in C. elegansZinc Levels Modulate Lifespan through Multiple Longevity Pathways in Caenorhabditis elegansBalanced trade-offs between alternative strategies shape the response of C. elegans reproduction to chronic heat stressLoss of a neural AMP-activated kinase mimics the effects of elevated serotonin on fat, movement, and hormonal secretionsHeritable transmission of stress resistance by high dietary glucose in Caenorhabditis elegansFolliculin regulates ampk-dependent autophagy and metabolic stress survivalDAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegansC. elegans are protected from lethal hypoxia by an embryonic diapauseTATN-1 mutations reveal a novel role for tyrosine as a metabolic signal that influences developmental decisions and longevity in Caenorhabditis elegansA neuromedin U receptor acts with the sensory system to modulate food type-dependent effects on C. elegans lifespanEnvironmental and genetic preconditioning for long-term anoxia responses requires AMPK in Caenorhabditis elegansResveratrol improves health and survival of mice on a high-calorie dietThe role of insulin/IGF-1 signaling in the longevity of model invertebrates, C. elegans and D. melanogasterChemical genetic screen for AMPKα2 substrates uncovers a network of proteins involved in mitosisDietary antiaging phytochemicals and mechanisms associated with prolonged survivalFunction of RSKS-1-AAK-2-DAF-16 signaling cascade in enhancing toxicity of multi-walled carbon nanotubes can be suppressed by mir-259 activation in Caenorhabditis elegansGenetics of aging in Caenorhabditis elegansMetformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1Novel protein kinase signaling systems regulating lifespan identified by small molecule library screening using DrosophilaActivation of AMPK by the putative dietary restriction mimetic metformin is insufficient to extend lifespan in DrosophilaEvolution in eggs and phases: experimental evolution of fecundity and reproductive timing in Caenorhabditis elegansC. elegans S6K Mutants Require a Creatine-Kinase-like Effector for Lifespan ExtensionAging and the Mammalian regulatory triumvirateSynthetic Ligands of Cannabinoid Receptors Affect Dauer Formation in the Nematode Caenorhabditis elegans
P2860
Q21563497-1000FF2F-4A11-40FD-B237-0B1F2567CEFBQ24329244-5A35E2E6-3407-420C-A010-3ACD72094588Q24609529-7E078675-A379-4430-AAD3-46541B1FCD83Q24610297-E87829B2-B131-4AC6-A4E7-FE2A2EBB581EQ24610741-0F34F21D-32B1-41E2-946E-214B0ACA74BAQ24633177-2690E98C-CC4C-449A-B1A4-640C8B3E94C3Q24633927-1CE35CDF-394E-4915-A94C-49CEEBE365A3Q24646027-90A707A3-B2E7-4FD7-95D8-F78C93D9FE78Q24811634-34C33F10-B226-4BA3-A26C-7A8F3F26466AQ26766053-8FBAD3DF-EB86-41A8-896C-D38A9ECD87F3Q26773901-8EBB92FD-D407-4F58-90EE-24D4AEA1A650Q26777180-4787C015-2637-4469-BF90-6A2749B58DBBQ26777407-120022A1-EDC2-408A-8E4C-B3842C785408Q26865723-197AF2B4-101E-45B6-AFD8-36B672429EA1Q27002908-7EDD682B-55F2-46D5-93A2-CFE934350757Q27310260-C554F956-8C91-4254-B6EE-180741A18C06Q27311025-7AF7DD14-FE5D-4BD6-9421-E07DF9E66C15Q27313811-8A0CC308-C235-489F-92FD-71081D0929D1Q27314433-FAD57C0A-676E-41AB-A4F5-136286E020A8Q27315375-06055ADB-A16C-4BA6-B219-47B9FCC87EB8Q27315866-86084E13-823F-4FD0-94FC-6DE0014EDDF7Q27316476-2E11069C-3C90-4639-99E3-1109C677F6EEQ27317096-D8FD3A0B-7A49-4004-B3DF-7BA5F96EBA82Q27317135-4AA4798C-AE0D-4B94-BA38-7DC85B6C9B0AQ27318316-E3DD559B-27DB-4912-BB21-DC8FB835E4D7Q27324458-AFC7CB98-B07D-4223-8C73-689D0CBEF464Q27437611-19C99B52-7F1C-4967-BEDD-1C255E395F45Q27860950-0269999E-A26E-4CCE-8951-F0403944722CQ28083445-D5DC312A-2DB9-461B-AB4A-DDEF9793D959Q28254513-C165394F-795E-4736-9E38-62C8D1A42AC2Q28385788-19EF298A-6794-484E-8107-5B1CF4011BACQ28387844-2C168E9E-43CA-46C2-A73B-89F145F6E2D0Q28469314-20C5CDB1-F037-4C9B-B68F-B57119B606CBQ28472548-0F3FE039-2B7B-43F1-9E7E-9E6791881B5BQ28480961-EDEF4F1C-B409-439C-AA3A-5D4C16A503BEQ28484435-3609551A-A12B-4D96-B2F2-534A6C74D4CCQ28584737-46A8A393-6F5F-4D45-A246-607A76805960Q28601083-9338D35B-58B3-44AA-A1BF-9E884A6F1EF6Q28731496-E21F1641-91E7-4261-8C1A-85957A3C4AD2Q28829473-14908BD4-087C-4955-9F64-156DA9DFB71F
P2860
The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
The AMP-activated protein kina ...... nals to lifespan in C. elegans
@en
type
label
The AMP-activated protein kina ...... nals to lifespan in C. elegans
@en
prefLabel
The AMP-activated protein kina ...... nals to lifespan in C. elegans
@en
P2093
P2860
P356
P1433
P1476
The AMP-activated protein kina ...... nals to lifespan in C. elegans
@en
P2093
Greg O'Connor
Peter S DiStefano
Rory Curtis
Tom McDonagh
P2860
P304
P356
10.1101/GAD.1255404
P50
P577
2004-12-01T00:00:00Z