A nonsecretable cell surface mutant of tumor necrosis factor (TNF) kills by cell-to-cell contact.
about
Pathogen recognition and activation of the innate immune response in zebrafishSPPL2a and SPPL2b promote intramembrane proteolysis of TNFalpha in activated dendritic cells to trigger IL-12 productionCell-cell adhesion mediated by binding of membrane-anchored ligand LERK-2 to the EPH-related receptor human embryonal kinase 2 promotes tyrosine kinase activityCrystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzymeAnti-TNF therapy for juvenile idiopathic arthritis-related uveitisStructural Basis for Treating Tumor Necrosis Factor (TNF )-associated Diseases with the Therapeutic Antibody InfliximabAssessment of Anti-TNF-α Activities in Keratinocytes Expressing Inducible TNF- α: A Novel Tool for Anti-TNF-α Drug ScreeningAnti-tumour effects of a specific anti-ADAM17 antibody in an ovarian cancer model in vivoMolecular interactions between T cells and fibroblast-like synoviocytes: role of membrane tumor necrosis factor-alpha on cytokine-activated T cells.Characterization of the baboon responses to Shiga-like toxin: descriptive study of a new primate model of toxic responses to Stx-1Active-site determinants of substrate recognition by the metalloproteinases TACE and ADAM10The potential for monocyte-mediated immunotherapy during infection and malignancy. Part I: apoptosis induction and cytotoxic mechanisms.Regulation of TH17 Cells and Associated Cytokines in Wound Healing, Tissue Regeneration, and Carcinogenesis.Humanization and characterization of an anti-human TNF-α murine monoclonal antibody.Opposing roles for membrane bound and soluble Fas ligand in glaucoma-associated retinal ganglion cell death.A casein kinase I motif present in the cytoplasmic domain of members of the tumour necrosis factor ligand family is implicated in 'reverse signalling'Transmembrane TNF-alpha: structure, function and interaction with anti-TNF agents.Transgenic models for cytokine-induced neurological disease.Role of TNF in lymphocyte-mediated cytotoxicity.Differential effects of interleukin-7 and interleukin-15 on NK cell anti-human immunodeficiency virus activity.Apoptosis in diseases of the liver.Membrane-bound TNF induces protective immune responses to M. bovis BCG infection: regulation of memTNF and TNF receptors comparing two memTNF molecules.Transmembrane kit ligand cleavage does not require a signal in the cytoplasmic domain and occurs at a site dependent on spacing from the membraneAnti-TNFα domain antibody construct CEP-37247: Full antibody functionality at half the size.The biosynthesis characteristics of TTP and TNF can be regulated through a posttranscriptional molecular loopReview article: the management of refractory Crohn's disease.Tumor necrosis factor-α signaling in macrophages.TNF-alpha and adipocyte biology.Crosstalk between immune cells and adipocytes requires both paracrine factors and cell contact to modify cytokine secretion.Characterization of golimumab, a human monoclonal antibody specific for human tumor necrosis factor α.The extracellular regulation of growth factor actionNovel Human Three-Domain Antibody Fragments Against sTNFα as Well as tmTNFα with High Affinity Generated by the Combination of Ribosome Display and E. coli Expression System.Activated release of membrane-anchored TGF-alpha in the absence of cytosol.Association of the transmembrane TGF-alpha precursor with a protein kinase complex.In vivo activity of tumor necrosis factor (TNF) mutants. Secretory but not membrane-bound TNF mediates the regression of retrovirally transduced murine tumorA metalloprotease inhibitor blocks shedding of the 80-kD TNF receptor and TNF processing in T lymphocytes.Opposing effects of transmembrane and soluble Fas ligand expression on inflammation and tumor cell survival.Natural killer (NK) cell-mediated cytotoxicity: differential use of TRAIL and Fas ligand by immature and mature primary human NK cellsSignaling of cytokines is important in regulation of GnRH neurons.Membrane-anchored heparin-binding EGF-like growth factor (HB-EGF) and diphtheria toxin receptor-associated protein (DRAP27)/CD9 form a complex with integrin alpha 3 beta 1 at cell-cell contact sites.
P2860
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P2860
A nonsecretable cell surface mutant of tumor necrosis factor (TNF) kills by cell-to-cell contact.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
A nonsecretable cell surface m ...... kills by cell-to-cell contact.
@en
type
label
A nonsecretable cell surface m ...... kills by cell-to-cell contact.
@en
prefLabel
A nonsecretable cell surface m ...... kills by cell-to-cell contact.
@en
P2093
P1433
P1476
A nonsecretable cell surface m ...... kills by cell-to-cell contact.
@en
P2093
P304
P356
10.1016/0092-8674(90)90158-B
P407
P577
1990-10-01T00:00:00Z