Relationship between expression levels and atherogenesis in scavenger receptor class B, type I transgenics.
about
Scavenger receptor class B type I is a multiligand HDL receptor that influences diverse physiologic systemsEffect of up-regulating individual steps in the reverse cholesterol transport pathway on reverse cholesterol transport in normolipidemic miceRare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart diseaseLoss of PDZK1 causes coronary artery occlusion and myocardial infarction in Paigen diet-fed apolipoprotein E deficient mice.Scavenger receptor BI facilitates hepatic very low density lipoprotein production in mice.Tryptophan 415 Is Critical for the Cholesterol Transport Functions of Scavenger Receptor BIRole of the adaptor protein PDZK1 in controlling the HDL receptor SR-BISerum opacity factor unmasks human plasma high-density lipoprotein instability via selective delipidation and apolipoprotein A-I desorption.Susceptibility gene for stroke or cerebral infarction in the Han population in Hunan Province of China.ATP Synthase β-Chain Overexpression in SR-BI Knockout Mice Increases HDL Uptake and Reduces Plasma HDL LevelHepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo.Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice.SR-BI/CD36 chimeric receptors define extracellular subdomains of SR-BI critical for cholesterol transport.Streptococcal serum opacity factor increases the rate of hepatocyte uptake of human plasma high-density lipoprotein cholesterolDiscovery of chemical inhibitors of the selective transfer of lipids mediated by the HDL receptor SR-BI.Functional characterization of newly-discovered mutations in human SR-BIExpression, purification and reconstitution of the C-terminal transmembrane domain of scavenger receptor BI into detergent micelles for NMR analysis.Scavenger receptor BI (SR-BI) clustered on microvillar extensions suggests that this plasma membrane domain is a way station for cholesterol trafficking between cells and high-density lipoprotein.A Western-fed diet increases plasma HDL and LDL-cholesterol levels in apoD-/- mice.Cholesteryl ester transfer protein expression partially attenuates the adverse effects of SR-BI receptor deficiency on cholesterol metabolism and atherosclerosis.SR-BI in bone marrow derived cells protects mice from diet induced coronary artery atherosclerosis and myocardial infarction.Glycine dimerization motif in the N-terminal transmembrane domain of the high density lipoprotein receptor SR-BI required for normal receptor oligomerization and lipid transport.Knockdown expression and hepatic deficiency reveal an atheroprotective role for SR-BI in liver and peripheral tissuesDual role for scavenger receptor class B, type I on bone marrow-derived cells in atherosclerotic lesion development.Molecular regulation of HDL metabolism and function: implications for novel therapies.C323 of SR-BI is required for SR-BI-mediated HDL binding and cholesteryl ester uptake.Protein mediators of sterol transport across intestinal brush border membrane.Pharmacologic suppression of hepatic ATP-binding cassette transporter 1 activity in mice reduces high-density lipoprotein cholesterol levels but promotes reverse cholesterol transport.SR-BI and HDL cholesteryl ester metabolism.MLL histone methylases regulate expression of HDLR-SR-B1 in presence of estrogen and control plasma cholesterol in vivoIntestinal SR-BI does not impact cholesterol absorption or transintestinal cholesterol efflux in mice.Identification of the molecular target of small molecule inhibitors of HDL receptor SR-BI activity.Increased HDL cholesterol and apoA-I in humans and mice treated with a novel SR-BI inhibitor.Functional genomics of the human high-density lipoprotein receptor scavenger receptor BI: an old dog with new tricks.Scavenger receptor class B member 1 protein: hepatic regulation and its effects on lipids, reverse cholesterol transport, and atherosclerosis.HDL quality and functionality: what can proteins and genes predict?Identification of the N-linked glycosylation sites on the high density lipoprotein (HDL) receptor SR-BI and assessment of their effects on HDL binding and selective lipid uptake.Comparative safety evaluation of selective androgen receptor modulators and anabolic androgenic steroids.Scavenger receptor B1 (SR-B1) profoundly excludes high density lipoprotein (HDL) apolipoprotein AII as it nibbles HDL-cholesteryl ester.Rediscovering scavenger receptor type BI: surprising new roles for the HDL receptor.
P2860
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P2860
Relationship between expression levels and atherogenesis in scavenger receptor class B, type I transgenics.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Relationship between expressio ...... r class B, type I transgenics.
@en
type
label
Relationship between expressio ...... r class B, type I transgenics.
@en
prefLabel
Relationship between expressio ...... r class B, type I transgenics.
@en
P2093
P2860
P356
P1476
Relationship between expressio ...... r class B, type I transgenics.
@en
P2093
P2860
P304
20368-20373
P356
10.1074/JBC.M000730200
P407
P577
2000-07-01T00:00:00Z