Involvement of the PPPGHR motif in T cell activation via CD2.
about
Identification of a proline-binding motif regulating CD2-triggered T lymphocyte activationA cdc15-like adaptor protein (CD2BP1) interacts with the CD2 cytoplasmic domain and regulates CD2-triggered adhesion.Dynamic recruitment of human CD2 into lipid rafts. Linkage to T cell signal transductionDynamic interaction of CD2 with the GYF and the SH3 domain of compartmentalized effector moleculesNovel interaction partners of the CD2BP2-GYF domain.Recognition sequences for the GYF domain reveal a possible spliceosomal function of CD2BP2.Cloning and comparative analysis of the human pre-T-cell receptor alpha-chain gene.Identification of a proline-rich sequence in the CD2 cytoplasmic domain critical for regulation of integrin-mediated adhesion and activation of phosphoinositide 3-kinaseA role for phosphatidylinositol 3-kinase in the regulation of beta 1 integrin activity by the CD2 antigenT cell receptor-independent CD2 signal transduction in FcR+ cells.The GYF domain.Expression cloning of an equine T-lymphocyte glycoprotein CD2 cDNA. Structure-based analysis of conserved sequence elements.Separable portions of the CD2 cytoplasmic domain involved in signaling and ligand avidity regulation.Inhibition and activation by CD244 depends on CD2 and phospholipase C-gamma1
P2860
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P2860
Involvement of the PPPGHR motif in T cell activation via CD2.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Involvement of the PPPGHR motif in T cell activation via CD2.
@en
type
label
Involvement of the PPPGHR motif in T cell activation via CD2.
@en
prefLabel
Involvement of the PPPGHR motif in T cell activation via CD2.
@en
P2093
P2860
P356
P1476
Involvement of the PPPGHR motif in T cell activation via CD2.
@en
P2093
P2860
P304
P356
10.1084/JEM.172.1.351
P407
P577
1990-07-01T00:00:00Z