Dose-response relationship between O6-methylguanine formation in Clara cells and induction of pulmonary neoplasia in the rat by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
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Urinary tobacco smoke-constituent biomarkers for assessing risk of lung cancer.Alterations in the K-ras and p53 genes in rat lung tumorsQuantitation of pyridylhydroxybutyl-DNA adducts in liver and lung of F-344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.K-ras mutations in sinonasal cancers in relation to wood dust exposure.Formation and distribution of NNK metabolites in an isolated perfused rat lung.It is time to regulate carcinogenic tobacco-specific nitrosamines in cigarette tobacco.Formation, repair, and genotoxic properties of bulky DNA adducts formed from tobacco-specific nitrosamines.Lysyl oxidase, a critical intra- and extra-cellular target in the lung for cigarette smoke pathogenesis.Role of chemically induced cell proliferation in carcinogenesis and its use in health risk assessmentThe formation and biological significance of N7-guanine adductsNNK, a tobacco-specific carcinogen, inhibits the expression of lysyl oxidase, a tumor suppressor.Formation of DNA adducts and induction of mutations in rats treated with tumorigenic doses of 1,6-dinitropyrene.DNA adduct measurements and tumor incidence during chronic carcinogen exposure in rodentsSignificance of DNA adduct studies in animal models for cancer molecular dosimetry and risk assessment.Tobacco-specific nitrosamine adducts: studies in laboratory animals and humans.Assessing exposure to tobacco-specific carcinogen NNK using its urinary metabolite NNAL measured in US population: 2011-2012.Ultrastructural observations in copper-deficient guinea-pig lung cells.Urinary levels of volatile organic carcinogen and toxicant biomarkers in relation to lung cancer development in smokers.Formation and repair of pyridyloxobutyl DNA adducts and their relationship to tumor yield in A/J mice.Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosisO6-methylguanine-DNA methyltransferase protects against nitrosamine-induced hepatocarcinogenesis.A prospectively measured serum biomarker for a tobacco-specific carcinogen and lung cancer in smokers.Smokers with the CHRNA lung cancer-associated variants are exposed to higher levels of nicotine equivalents and a carcinogenic tobacco-specific nitrosamine.N-7-Alkyl-2'-Deoxyguanosine as surrogate biomarkers for N-nitrosamine exposure in human lung.4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) regulates CTL activation and memory programmingThirdhand tobacco smoke: a tobacco-specific lung carcinogen on surfaces in smokers' homes.Exposure to the carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in smokers from 3 populations with different risks of lung cancer.Cell-specific expression of CYP2A5 in the mouse respiratory tract: effects of olfactory toxicants.Context Matters: Contribution of Specific DNA Adducts to the Genotoxic Properties of the Tobacco-Specific Nitrosamine NNK.An analysis of the role of tobacco-specific nitrosamines in the carcinogenicity of tobacco smoke.Comparative levels of O6-methylguanine, pyridyloxobutyl-, and pyridylhydroxybutyl-DNA adducts in lung and liver of rats treated chronically with the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.Metastasis to the F344 Rat Pancreas from Lung Cancer Induced by 4-(Methylnitrosamino)- 1-(3-pyridyl)-1-butanone and Enantiomers of Its Metabolite 4-(Methylnitrosamino)-1-(3-pyridyl)- 1-butanol, Constituents of Tobacco Products.Role of point mutation of the K-ras gene in tumorigenesis of B6C3F1 mouse lung lesions induced by urethane.Effects of K-ras gene mutations in the development of lung lesions induced by 4-(N-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone in A/J mice.Effect of a 12-week submaximal swimming training in rats exposed to tobacco- derived nitrosamine ketone.Protection against malignant progression of spontaneously developing liver tumors in transgenic mice expressing O(6)-methylguanine-DNA methyltransferase.
P2860
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P2860
Dose-response relationship between O6-methylguanine formation in Clara cells and induction of pulmonary neoplasia in the rat by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Dose-response relationship bet ...... ino)-1-(3-pyridyl)-1-butanone.
@en
type
label
Dose-response relationship bet ...... ino)-1-(3-pyridyl)-1-butanone.
@en
prefLabel
Dose-response relationship bet ...... ino)-1-(3-pyridyl)-1-butanone.
@en
P2093
P1433
P1476
Dose-response relationship bet ...... mino)-1-(3-pyridyl)-1-butanone
@en
P2093
M W Anderson
R R Maronpot
S A Belinsky
P304
P407
P577
1990-06-01T00:00:00Z