A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis. - Wikidata - awgldk - TriplyDB

A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis.

A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis.

http://www.wikidata.org/entity/Q41738233

about

TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits Prioritizing Approaches to Engage Community Members and Build Trust in Biobanks: A Survey of Attitudes and Opinions of Adults within Outpatient Practices at the University of Maryland Exome sequencing identifies a novel multiple sclerosis susceptibility variant in the TYK2 gene Genotyping of immune-related genetic variants identifies TYK2 as a novel associated locus for idiopathic inflammatory myopathies.Meta-analysis of genetic polymorphisms in granulomatosis with polyangiitis (Wegener's) reveals shared susceptibility loci with rheumatoid arthritis Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls.IL12A, MPHOSPH9/CDK2AP1 and RGS1 are novel multiple sclerosis susceptibility loci.Regulatory T-cell as orchestra leader in immunosuppression process of multiple sclerosis.Risk conferring genes in multiple sclerosis.Genetic insights into common pathways and complex relationships among immune-mediated diseases.Interferons in the central nervous system: a few instruments play many tunes.Therapeutic potential of tyrosine kinase 2 in autoimmunity.The Norwegian Multiple Sclerosis Registry and Biobank.CD6 gene polymorphism rs17824933 is associated with multiple sclerosis in Indian population.Canonical and Non-Canonical Aspects of JAK-STAT Signaling: Lessons from Interferons for Cytokine Responses.Simian immunodeficiency virus infection in the brain and lung leads to differential type I IFN signaling during acute infection.Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations.Identifying consistent allele frequency differences in studies of stratified populations.Meta-analysis of TYK2 gene polymorphisms association with susceptibility to autoimmune and inflammatory diseases.The psoriasis-protective TYK2 I684S variant impairs IL-12 stimulated pSTAT4 response in skin-homing CD4+ and CD8+ memory T-cells.

P2860

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P2860

A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis.

http://www.wikidata.org/entity/Q41738233

description

2009 nî lūn-bûn

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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2009年论文

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2009年论文

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name

A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis.

@en

type

label

A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis.

@en

prefLabel

A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis.

@en

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European Journal of Human Genetics

P1476

A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis.

@en

P2093

Annette Bang Oturai

http://www.w3.org/2001/XMLSchema#string

Anu Kemppinen

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Aslaug R Lorentzen

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Benedicte A Lie

http://www.w3.org/2001/XMLSchema#string

Cathrine Smestad

http://www.w3.org/2001/XMLSchema#string

Elisabeth G Celius

http://www.w3.org/2001/XMLSchema#string

Hanne F Harbo

http://www.w3.org/2001/XMLSchema#string

Helle Bach Søndergaard

http://www.w3.org/2001/XMLSchema#string

Inger-Lise Mero

http://www.w3.org/2001/XMLSchema#string

Irina Elovaara

http://www.w3.org/2001/XMLSchema#string

P2860

Recommended diagnostic criteria for multiple sclerosis: Guidelines from the international panel on the diagnosis of multiple sclerosis

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

PLINK: a tool set for whole-genome association and population-based linkage analyses

Haploview: analysis and visualization of LD and haplotype maps

Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis

Risk alleles for multiple sclerosis identified by a genomewide study

Replication of recently identified systemic lupus erythematosus genetic associations: a case-control study.

Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data.

New diagnostic criteria for multiple sclerosis: guidelines for research protocols.

Genome-wide association studies: theoretical and practical concerns.

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502-504

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scholarly article

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10.1038/EJHG.2009.195

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4

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18

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Finn Sellebjerg

Frank Dudbridge

Kjell-Morten Myhr

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2009-11-04T00:00:00Z

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38066067

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19888296

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multiple sclerosis

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2987240

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