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A hexadecylamide derivative of hyaluronan (HYMOVIS®) has superior beneficial effects on human osteoarthritic chondrocytes and synoviocytes than unmodified hyaluronanThe Importance of CD44 as a Stem Cell Biomarker and Therapeutic Target in CancerSize Matters: Molecular Weight Specificity of Hyaluronan Effects in Cell BiologyUtilization of Glycosaminoglycans/Proteoglycans as Carriers for Targeted Therapy DeliveryInteractions between Hyaluronan and Its Receptors (CD44, RHAMM) Regulate the Activities of Inflammation and CancerStructural Basis for CD44 Recognition by ERM ProteinsInducible hyaluronan production reveals differential effects on prostate tumor cell growth and tumor angiogenesisInteraction of low molecular weight hyaluronan with CD44 and toll-like receptors promotes the actin filament-associated protein 110-actin binding and MyD88-NFκB signaling leading to proinflammatory cytokine/chemokine production and breast tumor invaInhibition of the plasma membrane Ca2+ pump by CD44 receptor activation of tyrosine kinases increases the action potential afterhyperpolarization in sensory neuronsCooperative roles for emmprin and LYVE-1 in the regulation of chemoresistance for primary effusion lymphoma.CD147, CD44, and the epidermal growth factor receptor (EGFR) signaling pathway cooperate to regulate breast epithelial cell invasiveness.Abrogating drug resistance in malignant peripheral nerve sheath tumors by disrupting hyaluronan-CD44 interactions with small hyaluronan oligosaccharides.Hyaluronan, CD44, and emmprin regulate lactate efflux and membrane localization of monocarboxylate transporters in human breast carcinoma cellsAnalysis of CD44-hyaluronan interactions in an artificial membrane system: insights into the distinct binding properties of high and low molecular weight hyaluronanInhibition of Functional Hyaluronan-CD44 Interactions in CD133-positive Primary Human Ovarian Carcinoma Cells by Small Hyaluronan Oligosaccharides.Development of drug loaded nanoparticles for tumor targeting. Part 1: Synthesis, characterization, and biological evaluation in 2D cell cultures.Hyaluronan Depolymerization by Megakaryocyte Hyaluronidase-2 Is Required for Thrombopoiesis.Isothiocyanate analogs targeting CD44 receptor as an effective strategy against colon cancerThe impact of hyaluronic acid oligomer content on physical, mechanical, and biologic properties of divinyl sulfone-crosslinked hyaluronic acid hydrogels.Chemically modified N-acylated hyaluronan fragments modulate proinflammatory cytokine production by stimulated human macrophages.Low molecular weight hyaluronan-pulsed human dendritic cells showed increased migration capacity and induced resistance to tumor chemoattraction.Hyaluronan binding motifs of USP17 and SDS3 exhibit anti-tumor activity.ECM components guide IL-10 producing regulatory T-cell (TR1) induction from effector memory T-cell precursors.A role for CD44 in an antigen-induced murine model of pulmonary eosinophilia.Intraperitoneal delivery of platinum with in-situ crosslinkable hyaluronic acid gel for local therapy of ovarian cancer.Role of hyaluronan and hyaluronan-binding proteins in lung pathobiology.Hyaluronan-CD44 interactions as potential targets for cancer therapy.The nicotinic receptor Alpha7 impacts the mouse lung response to LPS through multiple mechanisms.Involvement of endothelial CD44 during in vivo angiogenesis.Hyaluronan fragments as mediators of inflammation in allergic pulmonary diseaseCD44 and HCELL: preventing hematogenous metastasis at step 1.Interleukin-1β-induced Reduction of CD44 Ser-325 Phosphorylation in Human Epidermal Keratinocytes Promotes CD44 Homomeric Complexes, Binding to Ezrin, and Extended, Monocyte-adhesive Hyaluronan Coats.Mechanisms involved in enhancement of the expression and function of aggrecanases by hyaluronan oligosaccharidesDesign and syntheses of hyaluronan oligosaccharide conjugates as inhibitors of CD44-Hyaluronan binding.Perturbation of hyaluronan interactions inhibits malignant properties of glioma cellsSubstitution of Heavy Complementarity Determining Region 3 (CDR-H3) Residues Can Synergistically Enhance Functional Activity of Antibody and Its Binding Affinity to HER2 Antigen.Carboxymethyl Hyaluronan-Stabilized Nanoparticles for Anticancer Drug Delivery.Hyaluronan Oligosaccharides Induce MMP-1 and -3 via Transcriptional Activation of NF-κB and p38 MAPK in Rheumatoid Synovial FibroblastsDoxorubicin-Hyaluronan Conjugated Super-Paramagnetic Iron Oxide Nanoparticles (DOX-HA-SPION) Enhanced Cytoplasmic Uptake of Doxorubicin and Modulated Apoptosis, IL-6 Release and NF-kappaB Activity in Human MDA-MB-231 Breast Cancer Cells.The high and low molecular weight forms of hyaluronan have distinct effects on CD44 clustering.
P2860
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P2860
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Hyaluronan binding by cell surface CD44.
@en
type
label
Hyaluronan binding by cell surface CD44.
@en
prefLabel
Hyaluronan binding by cell surface CD44.
@en
P2093
P356
P1476
Hyaluronan binding by cell surface CD44.
@en
P2093
P304
26967-26975
P356
10.1074/JBC.M002527200
P407
P577
2000-09-01T00:00:00Z