Novel Series of Potent Glucokinase Activators Leading to the Discovery of AM-2394.

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Novel Series of Potent Glucokinase Activators Leading to the Discovery of AM-2394.

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2016 nî lūn-bûn

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2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

@zh

2016年论文

@zh-cn

name

Novel Series of Potent Glucokinase Activators Leading to the Discovery of AM-2394.

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Item

label

Novel Series of Potent Glucokinase Activators Leading to the Discovery of AM-2394.

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prefLabel

Novel Series of Potent Glucokinase Activators Leading to the Discovery of AM-2394.

@en

P1476

Novel Series of Potent Glucokinase Activators Leading to the Discovery of AM-2394.

@en

P2093

Alan Cheng

http://www.w3.org/2001/XMLSchema#string

Christopher F Kraser

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Eric Tien

http://www.w3.org/2001/XMLSchema#string

Jonathan Houze

http://www.w3.org/2001/XMLSchema#string

Julio C Medina

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Kevin R Condroski

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Lixia Jin

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Marion Conn

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Murielle Veniant-Ellison

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Paul J Dransfield

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P2860

Molecular physiology of mammalian glucokinase

Identification of a new class of glucokinase activators through structure-based design

Discovery of 2-pyridylureas as glucokinase activators

Present status of clinical deployment of glucokinase activators

Effects of MK-0941, a novel glucokinase activator, on glycemic control in insulin-treated patients with type 2 diabetes

C5-Alkyl-2-methylurea-Substituted Pyridines as a New Class of Glucokinase Activators.

Assessing the potential of glucokinase activators in diabetes therapy.

Characterization of a novel glucokinase activator in rat and mouse models

Glucokinase as glucose sensor and metabolic signal generator in pancreatic beta-cells and hepatocytes.

Piragliatin (RO4389620), a novel glucokinase activator, lowers plasma glucose both in the postabsorptive state and after a glucose challenge in patients with type 2 diabetes mellitus: a mechanistic study.

P304

714-718

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P31

scholarly article

P356

10.1021/ACSMEDCHEMLETT.6B00140

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P577

2016-05-23T00:00:00Z

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P698

27437083

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P932

4948016

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