The major histocompatibility complex-restricted antigen receptor on T cells. II. Role of the L3T4 product.
about
The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complexA second subunit of CD8 is expressed in human T cellsDouble-negative T cells during HIV/SIV infections: potential pinch hitters in the T-cell lineupDUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymesActivated lck tyrosine protein kinase stimulates antigen-independent interleukin-2 production in T cells.Alpha/beta T-cell antigen receptor gene and protein expression occurs at early stages of thymocyte differentiation.Class II MHC molecules and the HIV gp 120 envelope protein interact with functionally distinct regions of the CD4 moleculeAnti-L3T4 antibody inhibits the lysis of H-2 class II antigen-negative target cells by L3T4+ cytotoxic T lymphocytesThe T-cell accessory molecule CD4 recognizes a monomorphic determinant on isolated Ia.Structure of the T-cell antigen receptor: evidence for two CD3 epsilon subunits in the T-cell receptor-CD3 complexPhysical association of CD4 and the T-cell receptor can be induced by anti-T-cell receptor antibodiesCharacterization of immature thymocyte lines derived from T-cell receptor or recombination activating gene 1 and p53 double mutant mice.Role of CD4 molecule in the induction of interleukin 2 and interleukin 2 receptor in class II major histocompatibility complex-restricted antigen-specific T helper clones. T cell receptor/CD3 complex transmits CD4-dependent and CD4-independent signaDeletion of the cytoplasmic region of the CD3 epsilon subunit does not prevent assembly of a functional T-cell receptor.T-cell receptor-CD4 physical association in a murine T-cell hybridoma: induction by antigen receptor ligationStructure of the mouse gene encoding CD4 and an unusual transcript in brain.Coaggregation of the T-cell receptor with CD4 and other T-cell surface molecules enhances T-cell activation.The peptide specificity of the endogenous T follicular helper cell repertoire generated after protein immunization.Impaired survival of T helper cells in the absence of CD4.The H1 histamine receptor regulates allergic lung responses.Human immunodeficiency virus type 1 gp120 mimics a hidden monomorphic epitope borne by class I major histocompatibility complex heavy chains.Lymphocyte major histocompatibility complex-encoded class II structures may act as sperm receptors.Ghrelin augments murine T-cell proliferation by activation of the phosphatidylinositol-3-kinase, extracellular signal-regulated kinase and protein kinase C signaling pathwaysCD4 on the road to coreceptor status.Theoretical and practical aspects of antigenized antibodies.The coreceptor CD4 is expressed in distinct nanoclusters and does not colocalize with T-cell receptor and active protein tyrosine kinase p56lckStaphylococcal enterotoxin A and toxic shock syndrome toxin compete with CD4 for human major histocompatibility complex class II binding.Involvement of Lyt-2 and L3T4 in activation of hapten-specific Lyt-2+ L3T4+ T-cell clones.Partial primary structure of the T4 antigens of mouse and sheep: assignment of intrachain disulfide bonds.The T cell antigen receptor CD3:CD4 molecular complex is diminished on the surface of pulmonary lymphocytesSystemic mononuclear-cell vasculitis in MRL/Mp-lpr/lpr mice. A histologic and immunocytochemical analysis.Repression of human immunodeficiency virus type 1 long terminal repeat-driven gene expression by binding of the virus to its primary cellular receptor, the CD4 molecule.A CD8 polypeptide that is lost after passing the Golgi but before reaching the cell surface: a novel sorting mechanism.The CD4 molecule is not always required for the T cell response to bacterial enterotoxins.The CD3 zeta cytoplasmic domain mediates CD2-induced T cell activation.The major histocompatibility complex-restricted antigen receptor on T cells. IV. An antiidiotypic antibody predicts both antigen and I-specificityThe role of L3T4 in recognition of Ia by a cytotoxic, H-2Dd-specific T cell hybridoma.The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotypeMembrane Ia expression and antigen-presenting accessory cell function of L cells transfected with class II major histocompatibility complex genes.T cell receptors for responses to Mls determinants and allo-H-2 determinants appear to be encoded on different chromosomes
P2860
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P2860
The major histocompatibility complex-restricted antigen receptor on T cells. II. Role of the L3T4 product.
description
1983 nî lūn-bûn
@nan
1983年の論文
@ja
1983年論文
@yue
1983年論文
@zh-hant
1983年論文
@zh-hk
1983年論文
@zh-mo
1983年論文
@zh-tw
1983年论文
@wuu
1983年论文
@zh
1983年论文
@zh-cn
name
The major histocompatibility c ...... II. Role of the L3T4 product.
@en
type
label
The major histocompatibility c ...... II. Role of the L3T4 product.
@en
prefLabel
The major histocompatibility c ...... II. Role of the L3T4 product.
@en
P2093
P2860
P356
P1476
The major histocompatibility c ...... II. Role of the L3T4 product.
@en
P2093
P2860
P304
P356
10.1084/JEM.158.4.1077
P407
P577
1983-10-01T00:00:00Z