Lessons from free energy simulations of delta-opioid receptor homodimers involving the fourth transmembrane helix.
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Computational approaches for modeling GPCR dimerizationPreferred supramolecular organization and dimer interfaces of opioid receptors from simulated self-associationShowcasing modern molecular dynamics simulations of membrane proteins through G protein-coupled receptors.Membrane driven spatial organization of GPCRs.Making structural sense of dimerization interfaces of delta opioid receptor homodimers.Assessing the relative stability of dimer interfaces in g protein-coupled receptors.Exploring binding properties of agonists interacting with a δ-opioid receptor.Methods used to study the oligomeric structure of G-protein-coupled receptors.Differential stability of the crystallographic interfaces of mu- and kappa-opioid receptorsImpact of Lipid Composition and Receptor Conformation on the Spatio-temporal Organization of μ-Opioid Receptors in a Multi-component Plasma Membrane Model.The prevalence, maintenance, and relevance of G protein-coupled receptor oligomerizationMolecular Pharmacology of δ-Opioid Receptors.Novel structural and functional insights into M3 muscarinic receptor dimer/oligomer formation.Functional relevance of μ-δ opioid receptor heteromerization: a role in novel signaling and implications for the treatment of addiction disorders: from a symposium on new concepts in mu-opioid pharmacology.Beyond standard molecular dynamics: investigating the molecular mechanisms of G protein-coupled receptors with enhanced molecular dynamics methods.An Ensemble-Based Protocol for the Computational Prediction of Helix-Helix Interactions in G Protein-Coupled Receptors using Coarse-Grained Molecular DynamicsThe dopamine D2 receptor dimer and its interaction with homobivalent antagonists: homology modeling, docking and molecular dynamicsMulti-Component Protein - Protein Docking Based Protocol with External Scoring for Modeling Dimers of G Protein-Coupled Receptors.Excessive aggregation of membrane proteins in the Martini model.Molecular Dynamics Simulations of G Protein-Coupled Receptors.Closely related, yet unique: Distinct homo- and heterodimerization patterns of G protein coupled chemokine receptors and their fine-tuning by cholesterol.Molecular details of dimerization kinetics reveal negligible populations of transient µ-opioid receptor homodimers at physiological concentrations.
P2860
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P2860
Lessons from free energy simulations of delta-opioid receptor homodimers involving the fourth transmembrane helix.
description
2010 nî lūn-bûn
@nan
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
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2010年论文
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name
Lessons from free energy simul ...... he fourth transmembrane helix.
@en
type
label
Lessons from free energy simul ...... he fourth transmembrane helix.
@en
prefLabel
Lessons from free energy simul ...... he fourth transmembrane helix.
@en
P2860
P356
P1433
P1476
Lessons from free energy simul ...... he fourth transmembrane helix.
@en
P2093
Davide Provasi
Jennifer M Johnston
P2860
P304
P356
10.1021/BI100686T
P407
P577
2010-08-01T00:00:00Z