The rediscovery of HepG2 cells for prediction of drug induced liver injury (DILI).

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2014 nî lūn-bûn

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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2014年论文

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2014年论文

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name

The rediscovery of HepG2 cells for prediction of drug induced liver injury (DILI).

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The rediscovery of HepG2 cells for prediction of drug induced liver injury (DILI).

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The rediscovery of HepG2 cells for prediction of drug induced liver injury (DILI).

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P1476

The rediscovery of HepG2 cells for prediction of drug induced liver injury (DILI).

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P2093

Ahmed Ghallab

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P2860

Ethionine toxicity in vitro: the correlation of data from rat hepatocyte suspensions and monolayers with in vivo observations.

Cryopreserved primary hepatocytes as a constantly available in vitro model for the evaluation of human and animal drug metabolism and enzyme induction.

Primary hepatocytes: current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies.

Cell lines: a tool for in vitro drug metabolism studies.

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.

In Vitro Analysis of CsA-Induced Hepatotoxicity in HepG2 Cell Line: Oxidative Stress and α2 and β1 Integrin Subunits Expression.

Free radical generation from an aniline derivative in HepG2 cells: a possible captodative effect.

A 3D in vitro model of differentiated HepG2 cell spheroids with improved liver-like properties for repeated dose high-throughput toxicity studies.

An insight into the hepatocellular death induced by amphetamines, individually and in combination: the involvement of necrosis and apoptosis.

HepG2 cells simultaneously expressing five P450 enzymes for the screening of hepatotoxicity: identification of bioactivable drugs and the potential mechanism of toxicity involved.

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1286-1288

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2014-12-15T00:00:00Z

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26417344

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rediscovery

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4464501

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