Beta-catenin controls differentiation of the retinal pigment epithelium in the mouse optic cup by regulating Mitf and Otx2 expression
about
Neuroretina specification in mouse embryos requires Six3-mediated suppression of Wnt8b in the anterior neural plateEye morphogenesis and patterning of the optic vesicleStem Cell Therapy for Treatment of Ocular DisordersWNT/β-Catenin Signaling in Vertebrate Eye DevelopmentEye development and retinogenesisAP-2alpha knockout mice exhibit optic cup patterning defects and failure of optic stalk morphogenesisTranscription factor SOX9 plays a key role in the regulation of visual cycle gene expression in the retinal pigment epitheliumReprogramming of the chick retinal pigmented epithelium after retinal injuryCOUP-TFs regulate eye development by controlling factors essential for optic vesicle morphogenesis.PAX6 regulates melanogenesis in the retinal pigmented epithelium through feed-forward regulatory interactions with MITF.Putting regeneration into regenerative medicine.Role of heparan sulfate proteoglycans in optic disc and stalk morphogenesisA regulatory loop involving PAX6, MITF, and WNT signaling controls retinal pigment epithelium development.Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.The expression of Wnt2b in the optic cup lip requires a border between the pigmented and nonpigmented epithelium.The Wnt/β-catenin pathway cross-talks with STAT3 signaling to regulate survival of retinal pigment epithelium cells.Otx but not Mitf transcription factors are required for zebrafish retinal pigment epithelium development.Otx2 is involved in the regional specification of the developing retinal pigment epithelium by preventing the expression of sox2 and fgf8, factors that induce neural retina differentiation.Cadherin-mediated cell adhesion is critical for the closing of the mouse optic fissure.Vax1/2 genes counteract Mitf-induced respecification of the retinal pigment epitheliumUnderstanding the role of growth factors in embryonic development: insights from the lensEctopic Mitf in the embryonic chick retina by co-transfection of β-catenin and Otx2Multiple requirements of the focal dermal hypoplasia gene porcupine during ocular morphogenesisActivation of Wnt/β-catenin signaling in Muller glia protects photoreceptors in a mouse model of inherited retinal degeneration.Canonical Wnt/β-catenin signalling is essential for optic cup formationWnt ligands from the embryonic surface ectoderm regulate 'bimetallic strip' optic cup morphogenesis in mouseβ-Catenin inactivation is a pre-requisite for chick retina regeneration.CRIM1 haploinsufficiency causes defects in eye development in human and mouse.Genetic chimeras reveal the autonomy requirements for Vsx2 in embryonic retinal progenitor cells.Regulation of the human tyrosinase gene in retinal pigment epithelium cells: the significance of transcription factor orthodenticle homeobox 2 and its polymorphic binding siteMiR-204 is responsible for inherited retinal dystrophy associated with ocular colobomaEvidence for baseline retinal pigment epithelium pathology in the Trp1-Cre mouse.Prostaglandin E(2) mediates proliferation and chloride secretion in ADPKD cystic renal epithelia.Deficient FGF signaling causes optic nerve dysgenesis and ocular colobomaLoss of Axin2 Causes Ocular Defects During Mouse Eye DevelopmentEmbryonic markers of cone differentiation.Activated monocytes resist elimination by retinal pigment epithelium and downregulate their OTX2 expression via TNF-α.Compartmentalization of vertebrate optic neuroephithelium: external cues and transcription factors.Retinal pigment epithelium development, plasticity, and tissue homeostasis.Genetic regulation of vertebrate eye development.
P2860
Q24598583-D58ECBF4-47F8-4D37-850D-868FAB4EF39BQ24629124-497FDC40-0F40-40AF-85B5-C8DA4AE5A8A2Q26746974-429E9BEB-ED06-45C2-80AC-BAC74BD4EE5DQ28067057-9FC3EB80-8D3C-4E23-A8FF-DA06DFE4E3FCQ28277172-FBB776DE-E6E0-439E-A956-EA8096FA4A62Q28510294-2112578E-4F81-4429-8A22-5E6344BEC1C8Q33556300-D23707C7-8307-451D-B744-848DA8471048Q33634435-EB6F072D-DE8B-4CD1-9168-ACEB04D84C85Q33684591-7E63BB35-08FB-4747-A286-149F02B98F5BQ33685468-C1901243-6F0E-4F2B-832D-89711777B83DQ33818931-C0DCB3B0-9536-43F4-B0AF-1FD91DA88977Q34254879-5DF93B10-19AA-4FDB-9A12-4C87EB9BA6D0Q34335517-093F1060-B012-4685-8794-4CB9194E1F5BQ34396844-B0C57AC1-21E4-44E2-AA3E-AAC1DA320C2AQ34410748-252DE44C-9CC1-41ED-BF02-6457572EBCDAQ34442425-EE520C1B-DD27-4780-996C-7A39A56EF777Q34472211-C05A889F-B5D1-4AA7-A7B9-E73481131C40Q34473649-5B2773C8-DD36-429A-9B79-C1B940131F39Q34512575-6C8CC109-61F4-4960-96AF-F37E5303F4D0Q34648878-CED98A35-8CB0-4DDF-8E2A-DA96F2F6FDE5Q34699933-9DB86838-2BC8-449E-A720-409299D4615BQ34735455-AAE8745F-F6FC-48A8-ADDA-22CD31BBEE49Q34780843-CF0475AC-8B04-4053-96EC-7B9891681EC5Q35034360-0A54205A-6135-49F2-B8D8-D025F70A2F71Q35063893-5047154B-50CE-486B-9B56-303D7B3185D5Q35157491-26325FAF-C1A0-4048-8DC0-D53613CAC5F2Q35202974-D25FF2E4-FA83-4187-B3F7-860492DA9F2BQ35234102-977E5E21-CE2C-4B9E-8DFD-710CBD7898ABQ35669528-3DA3A185-5589-497F-AD47-8C4F62E52BC0Q35673412-936C709B-64FE-4D72-BEAA-392685801AA6Q35796031-822BC289-B106-48E7-8BEE-B0BA7D95F7F7Q35951856-6BE43CD8-D325-4152-9C18-FD0287D3508AQ36454166-963EBB84-B437-4B6B-898F-01E8E66E0262Q36918086-0C3283F7-F706-465D-A9F2-F1449A7A86BCQ37320011-737C3939-7D03-4502-BD72-F1FEA4C58BC4Q37526805-0D015C4F-020F-4A8C-924B-CD4B4B3ADA31Q37592013-95E79557-B000-4020-82A0-851890CE176FQ37997316-80759D7E-1D19-486B-891D-72F1B1262FA6Q38141303-D2F87B3C-67C6-4D58-B48B-D771E14499EDQ38244962-63A9BC29-0A80-49A8-9C3C-392D6E7BD1F5
P2860
Beta-catenin controls differentiation of the retinal pigment epithelium in the mouse optic cup by regulating Mitf and Otx2 expression
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Beta-catenin controls differen ...... ating Mitf and Otx2 expression
@en
type
label
Beta-catenin controls differen ...... ating Mitf and Otx2 expression
@en
prefLabel
Beta-catenin controls differen ...... ating Mitf and Otx2 expression
@en
P2860
P356
P1433
P1476
Beta-catenin controls differen ...... ating Mitf and Otx2 expression
@en
P2093
Sabine Fuhrmann
Stefano Piccolo
P2860
P304
P356
10.1242/DEV.032136
P407
P577
2009-06-24T00:00:00Z