A mutation in Dbf4 motif M impairs interactions with DNA replication factors and confers increased resistance to genotoxic agents.
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Interactions of the human MCM-BP protein with MCM complex components and Dbf4Saccharomyces cerevisiae Dbf4 Has Unique Fold Necessary for Interaction with Rad53 KinaseMechanisms Governing DDK Regulation of the Initiation of DNA ReplicationA quantitative model of the initiation of DNA replication in Saccharomyces cerevisiae predicts the effects of system perturbations.The C-terminus of S. pombe DDK subunit Dfp1 is required for meiosis-specific transcription and cohesin cleavage.Integrin alpha5beta1 function is regulated by XGIPC/kermit2 mediated endocytosis during Xenopus laevis gastrulation.Phosphorylation of Mcm2 modulates Mcm2-7 activity and affects the cell's response to DNA damageThe role of Dbf4-dependent protein kinase in DNA polymerase ζ-dependent mutagenesis in Saccharomyces cerevisiae.A Dbf4p BRCA1 C-terminal-like domain required for the response to replication fork arrest in budding yeast.Concerted activities of Mcm4, Sld3, and Dbf4 in control of origin activation and DNA replication fork progressionDbf4: the whole is greater than the sum of its partsIncorporation into the prereplicative complex activates the Mcm2-7 helicase for Cdc7-Dbf4 phosphorylationCrystallization and preliminary X-ray diffraction analysis of motif N from Saccharomyces cerevisiae Dbf4Control over DNA replication in time and space.Differential chromatin proteomics of the MMS-induced DNA damage response in yeast.A synthetic human kinase can control cell cycle progression in budding yeast.Dbf4 and Cdc7 proteins promote DNA replication through interactions with distinct Mcm2-7 protein subunits.A novel non-canonical forkhead-associated (FHA) domain-binding interface mediates the interaction between Rad53 and Dbf4 proteins.Mcm10 deficiency causes defective-replisome-induced mutagenesis and a dependency on error-free postreplicative repair.Drug design with Cdc7 kinase: a potential novel cancer therapy target.Cdc7 is an active kinase in human cancer cells undergoing replication stress.
P2860
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P2860
A mutation in Dbf4 motif M impairs interactions with DNA replication factors and confers increased resistance to genotoxic agents.
description
2005 nî lūn-bûn
@nan
2005年の論文
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2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
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2005年论文
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name
A mutation in Dbf4 motif M imp ...... esistance to genotoxic agents.
@en
type
label
A mutation in Dbf4 motif M imp ...... esistance to genotoxic agents.
@en
prefLabel
A mutation in Dbf4 motif M imp ...... esistance to genotoxic agents.
@en
P2093
P2860
P1476
A mutation in Dbf4 motif M imp ...... esistance to genotoxic agents.
@en
P2093
Ajai A Prasad
Angela E Varrin
Matthew D Ramer
Rolf-Peter Scholz
P2860
P304
P356
10.1128/MCB.25.17.7494-7504.2005
P407
P577
2005-09-01T00:00:00Z