about
Imperfect coordination chemistry facilitates metal ion release in the Psa permeaseMolecular dynamics simulation of human prion protein including both N-linked oligosaccharides and the GPI anchor.A versatile synthetic approach toward diversity libraries using monosaccharide scaffolds.Molecular diversity through sugar scaffolds.Biological diversity from a structurally diverse library: systematically scanning conformational space using a pyranose scaffold.Drug-likeness and increased hydrophobicity of commercially available compound libraries for drug screening.Vancomycin: ligand recognition, dimerization and super-complex formation.Discovery of novel pneumococcal surface antigen A (PsaA) inhibitors using a fragment-based drug design approach.Metronidazole-triazole conjugates: activity against Clostridium difficile and parasitesCarbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activityTargeting Bacterial Cell Wall Peptidoglycan Synthesis by Inhibition of Glycosyltransferase Activity.The effect of environment on the recognition and binding of vancomycin to native and resistant forms of lipid II.Small-Molecule Inhibitors of the SOX18 Transcription Factor.Contribution of Amphipathicity and Hydrophobicity to the Antimicrobial Activity and Cytotoxicity of β-Hairpin PeptidesPharmacological targeting of the transcription factor SOX18 delays breast cancer in mice.Crystal structures of the PBP2 glycosyltransferase domain: new opportunities for antibacterial drug design.An evaluation of Minor Groove Binders as anti-fungal and anti-mycobacterial therapeutics.Helping Chemists Discover New Antibiotics.An azido-oxazolidinone antibiotic for live bacterial cell imaging and generation of antibiotic variants.Institutional profile: Community for Open Antimicrobial Drug Discovery - crowdsourcing new antibiotics and antifungals.Variation of the net charge, lipophilicity, and side chain flexibility in Dmt(1)-DALDA: Effect on Opioid Activity and Biodistribution.A probabilistic measure for alignment-free sequence comparison.Identification of antitubercular benzothiazinone compounds by ligand-based design.Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria.Membrane binding and perturbation studies of the antimicrobial peptides caerin, citropin, and maculatin.Structure aided design of chimeric antibioticsStructural model of human IL-13 defines the spatial interactions with the IL-13Ralpha/IL-4Ralpha receptorMetal complexes as a promising source for new antibiotics
P50
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P50
description
hulumtues
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researcher
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wetenschapper
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հետազոտող
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name
Johannes Zuegg
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Johannes Zuegg
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Johannes Zuegg
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Johannes Zuegg
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Johannes Zuegg
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type
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Johannes Zuegg
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Johannes Zuegg
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Johannes Zuegg
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Johannes Zuegg
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Johannes Zuegg
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Johannes Zuegg
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Johannes Zuegg
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Johannes Zuegg
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Johannes Zuegg
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Johannes Zuegg
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P1053
C-1347-2014
P106
P1153
6602888045
P2038
Johannes_Zuegg
P21
P31
P3829
P496
0000-0001-6240-6020