D-2-Hydroxyglutarate producing neo-enzymatic activity inversely correlates with frequency of the type of isocitrate dehydrogenase 1 mutations found in glioma
about
Genetics and Epigenetics of Glioblastoma: Applications and Overall Incidence of IDH1 MutationNew developments in the pathogenesis and therapeutic targeting of the IDH1 mutation in gliomaMetabolic consequences of oncogenic IDH mutationsRegistered report: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarateMutant IDH1 Dysregulates the Differentiation of Mesenchymal Stem Cells in Association with Gene-Specific Histone Modifications to Cartilage- and Bone-Related Genes.Quantitative Imaging of D-2-Hydroxyglutarate in Selected Histological Tissue Areas by a Novel Bioluminescence Technique.Decreased expression of IDH1-R132H correlates with poor survival in gastrointestinal cancer.Epigenetic silencing of XAF1 in high-grade gliomas is associated with IDH1 status and improved clinical outcome.Impending Impact of Molecular Pathology on Classifying Adult Diffuse Gliomas.Identification of a novel inactivating mutation in Isocitrate Dehydrogenase 1 (IDH1-R314C) in a high grade astrocytoma.Biological Significance of Mutant Isocitrate Dehydrogenase 1 and 2 in Gliomagenesis.Metabolomic comparison between cells over-expressing isocitrate dehydrogenase 1 and 2 mutants and the effects of an inhibitor on the metabolism.Targeting hexokinase 2 enhances response to radio-chemotherapy in glioblastoma.Studies on the Interaction of the Histone Demethylase KDM5B with Tricarboxylic Acid Cycle Intermediates.Clonal expansion and epigenetic reprogramming following deletion or amplification of mutant IDH1.Molecular mechanisms of isocitrate dehydrogenase 1 (IDH1) mutations identified in tumors: The role of size and hydrophobicity at residue 132 on catalytic efficiency.EZH2-, CHD4-, and IDH-linked epigenetic perturbation and its association with survival in glioma patients.Isocitrate dehydrogenase 1 mutation subtypes at site 132 and their translational potential in glioma.IDH1 Mutation and World Health Organization 2016 Diagnostic Criteria for Adult Diffuse Gliomas: Advances in Surgical Strategy.Rapid detection of 2-hydroxyglutarate in frozen sections of IDH mutant tumors by MALDI-TOF mass spectrometry.IDH1-mutated transgenic zebrafish lines: An in-vivo model for drug screening and functional analysis.
P2860
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P2860
D-2-Hydroxyglutarate producing neo-enzymatic activity inversely correlates with frequency of the type of isocitrate dehydrogenase 1 mutations found in glioma
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
D-2-Hydroxyglutarate producing ...... se 1 mutations found in glioma
@en
type
label
D-2-Hydroxyglutarate producing ...... se 1 mutations found in glioma
@en
prefLabel
D-2-Hydroxyglutarate producing ...... se 1 mutations found in glioma
@en
P2093
P2860
P50
P356
P1476
D-2-Hydroxyglutarate producing ...... se 1 mutations found in glioma
@en
P2093
Ann-Christin Beck
Johanna-Marie Lehmler
Jörg Balss
Leonille Schweizer
Susanne Weissert
P2860
P2888
P356
10.1186/2051-5960-2-19
P577
2014-02-14T00:00:00Z
P5875
P6179
1032667888