Sequential WT1 and CTNNB1 mutations and alterations of beta-catenin localisation in intralobar nephrogenic rests and associated Wilms tumours: two case studies.
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Is Wilms tumor a candidate neoplasia for treatment with WNT/β-catenin pathway modulators?--A report from the renal tumors biology-driven drug development workshopMolecular characterization of Wilms' tumor from a resource-constrained region of sub-Saharan AfricaFrequent long-range epigenetic silencing of protocadherin gene clusters on chromosome 5q31 in Wilms' tumor.Functional inactivation of the WTX gene is not a frequent event in Wilms' tumors.A novel Wilms tumor 1 (WT1) target gene negatively regulates the WNT signaling pathwayWilms tumor genetics: mutations in WT1, WTX, and CTNNB1 account for only about one-third of tumors.Deletions of 16q in Wilms tumors localize to blastemal-anaplastic cells and are associated with reduced expression of the IRXB renal tubulogenesis gene cluster.Wilms tumor suppressor, WT1, suppresses epigenetic silencing of the β-catenin gene.Wilms' tumours: about tumour suppressor genes, an oncogene and a chameleon gene.Comparative methylome analysis identifies new tumour subtypes and biomarkers for transformation of nephrogenic rests into Wilms tumourThe yin and yang of kidney development and Wilms' tumorsEstablishment of a Conditionally Immortalized Wilms Tumor Cell Line with a Homozygous WT1 Deletion within a Heterozygous 11p13 Deletion and UPD Limited to 11p15.Clinically relevant subsets identified by gene expression patterns support a revised ontogenic model of Wilms tumor: a Children's Oncology Group Study.Nephron Progenitor But Not Stromal Progenitor Cells Give Rise to Wilms Tumors in Mouse Models with β-Catenin Activation or Wt1 Ablation and Igf2 Upregulation.WT1 in disease: shifting the epithelial-mesenchymal balance.Priming the renal progenitor cell.Wilms Tumor Suppressor, WT1, Cooperates with MicroRNA-26a and MicroRNA-101 to Suppress Translation of the Polycomb Protein, EZH2, in Mesenchymal Stem Cells.Bilateral Wilms tumour: a review of clinical and molecular features.Wilms tumor cells with WT1 mutations have characteristic features of mesenchymal stem cells and express molecular markers of paraxial mesoderm.Perilobar nephrogenic rests are nonobligate molecular genetic precursor lesions of insulin-like growth factor-II-associated Wilms tumors.Wilms' tumor 1 gene (WT1) is overexpressed and provides an oncogenic function in pediatric nephroblastomas harboring the wild-type WT1The developmental programme for genesis of the entire kidney is recapitulated in Wilms tumour.WT1 Mutation in Childhood Cancer.
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P2860
Sequential WT1 and CTNNB1 mutations and alterations of beta-catenin localisation in intralobar nephrogenic rests and associated Wilms tumours: two case studies.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Sequential WT1 and CTNNB1 muta ...... lms tumours: two case studies.
@en
type
label
Sequential WT1 and CTNNB1 muta ...... lms tumours: two case studies.
@en
prefLabel
Sequential WT1 and CTNNB1 muta ...... lms tumours: two case studies.
@en
P2093
P2860
P356
P1476
Sequential WT1 and CTNNB1 muta ...... lms tumours: two case studies.
@en
P2093
Anthony E Reeve
Helen E More
Rosemary W Heathcott
Ryuji Fukuzawa
P2860
P304
P356
10.1136/JCP.2006.043083
P407
P577
2006-12-15T00:00:00Z